1019971-65-3Relevant articles and documents
5-tert-butyl-N-pyrazol-4-yl-4,5,6,7-tetrahydrobenzo[d]isoxazole-3- carboxamide derivatives as novel potent inhibitors of Mycobacterium tuberculosis pantothenate synthetase: Initiating a quest for new antitubercular drugs
Velaparthi, Subash,Brunsteiner, Michael,Uddin, Reaz,Wan, Baojie,Franzblau, Scott G.,Petukhov, Pavel A.
, p. 1999 - 2002 (2008/09/21)
Pantothenate synthetase (PS) is one of the potential new antimicrobial targets that may also be useful for the treatment of the nonreplicating persistent forms of Mycobacterium tuberculosis. In this Letter we present a series of 5-tert-butyl-N-pyrazol-4-y