102078-57-9

Basic information

• Product Name: p-chlorophenyl(phenyl)methyl p-tolyl sulfone
• Synonyms: p-chlorophenyl(phenyl)methyl p-tolyl sulfone
• CAS NO: 102078-57-9
• Molecular Weight: 356.873
• Mol File: 102078-57-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: p-chlorophenyl(phenyl)methyl p-tolyl sulfone(CAS DataBase Reference)
• NIST Chemistry Reference: p-chlorophenyl(phenyl)methyl p-tolyl sulfone(102078-57-9)
• EPA Substance Registry System: p-chlorophenyl(phenyl)methyl p-tolyl sulfone(102078-57-9)

Safety Data

• Hazardous Substances Data: 102078-57-9(Hazardous Substances Data)

Upstream product

• 637-87-6 1-Chloro-4-iodobenzene 
• 5395-20-0 1-methyl-4-(benzylsulfonyl)benzene 
• 119-56-2 (4-chlorophenyl)phenylmethanol 
• 38622-91-2 [(p-methylphenyl)sulfonylmethyl]isonitrile 
• 873-55-2 sodium benzenesulfonate 
• 108-86-1 bromobenzene 
• 104-88-1 4-chlorobenzaldehyde 
• 536-57-2 p-toluene sulfinic acid 

Relevant articles and documents

Substrate- and temperature-controlled divergence in reactions of alcohols with TosMIC catalyzed by BF3 · Et2O: Facile access to sulfinates and sulfones

An efficient BF3 · Et2O-catalyzed divergent synthesis of sulfinate esters and sulfones through C–O and C–S bond formation has been achieved from alcohols and p-toluenesulfonylmethyl isocyanide (TosMIC). Various alcohols reacted smoothly with TosMIC under the present conditions at room temperature providing sulfinate esters exclusively. By tuning the reaction temperature, the alcohols that provide highly stabilized carbocation in the reaction medium afforded sulfones as sole products. This study was aimed at understanding the regioselectivity of ambidentate sulfinate ion and to elucidate the interpretation of sulfinate/sulfone scaffolds.

Direct sulfonylation of Baylis-Hillman alcohols and diarylmethanols with TosMIC in ionic liquid-[Hmim]HSO4: An unexpected reaction

A Bronsted acidic ionic liquid-[Hmim]HSO4 promoted unexpected reaction of Baylis-Hillman alcohols and diarylmethanols with p-toluenesulfonylmethyl isocyanide (TosMIC) affording the corresponding sulfone derivatives instead of N-tosylmethyl amid