10212-13-2

Basic information

• Product Name: 3',5'-DI-O-ACETYL-2'-DEOXY-2'-FLUOROURIDINE
• Synonyms: 3',5'-DI-O-ACETYL-2'-DEOXY-2'-FLUOROURIDINE;2'-Deoxy-2'-fluoro-3',5'-di-O-acetyluridine
• CAS NO: 10212-13-2
• Molecular Formula: C₁₃H₁₅FN₂O₇
• Molecular Weight: 330.267
• Mol File: 10212-13-2.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: 3',5'-DI-O-ACETYL-2'-DEOXY-2'-FLUOROURIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3',5'-DI-O-ACETYL-2'-DEOXY-2'-FLUOROURIDINE(10212-13-2)
• EPA Substance Registry System: 3',5'-DI-O-ACETYL-2'-DEOXY-2'-FLUOROURIDINE(10212-13-2)

Safety Data

• Hazardous Substances Data: 10212-13-2(Hazardous Substances Data)

Usage

General Description

3',5'-DI-O-ACETYL-2'-DEOXY-2'-FLUOROURIDINE is a synthetic nucleoside analogue that has shown promise in the treatment of various types of cancer. It is an orally active prodrug of 2'-deoxy-2'-fluorouridine, which is a potent inhibitor of RNA synthesis and DNA replication in cancer cells. The compound is designed to be selectively activated in cancer cells, allowing for targeted destruction of the malignant tissue. Additionally, 3',5'-DI-O-ACETYL-2'-DEOXY-2'-FLUOROURIDINE has shown favorable pharmacokinetic properties, allowing for effective distribution and accumulation in tumor tissues. Further research and clinical trials are ongoing to assess the full potential of this compound in cancer therapy.

Upstream product

• 108-24-7 acetic anhydride 
• 56287-17-3 2'-deoxy-2'-fluorouridine 
• 64-19-7 acetic acid 

Downstream Products

• 1188523-13-8 3-(5'-O-dimethoxytrityl-2'-fluoro-2'-deoxy-β-D-ribofuranosyl)-9-(2-N-trifluoroacetamido-ethoxy)-1,3-diaza-2-oxophenoxazine 3'-O-(2-cyanoethyl)-N,N-diisopropylphosphoramidite 
• 1188523-08-1 3-(5'-O-dimethoxytrityl-2'-fluoro-2'-deoxy-β-D-ribofuranosyl)-9-(2-N-benzylcarbamyl-ethoxy)-1,3-diaza-2-oxophenoxazine 
• 1188523-11-6 3-(5'-O-dimethoxytrityl-2'-fluoro-2'-deoxy-β-D-ribofuranosyl)-9-(2-N-trifluoroacetamido-ethoxy)-1,3-diaza-2-oxophenoxazine 
• 1188523-00-3 3-(5'-O-dimethoxytrityl-2'-fluoro-2'-deoxy-β-D-ribofuranosyl)-1,3-diaza-2-oxophenoxazine 3'-O-(2-cyanoethyl)-N,N-diisopropylphosphoramidite 
• 1178552-81-2 3-(5'-O-dimethoxytrityl-2'-fluoro-2'-deoxy-β-D-ribofuranosyl)-9-(2-N-trifluoroacetamido-ethoxy)-1,3-diaza-2-oxophenoxazine 
• 1188523-04-7 5-bromo-3',5'-diacetyl-N₄-(2-(2-N-benzylcarbamyl-ethoxy)-6-hydroxyphenyl)-2'-fluoro-2'-deoxycytidine 
• 1174063-99-0 3-(5'-O-dimethoxytrityl-2'-fluoro-2'-deoxy-β-D-ribofuranosyl)-1,3-diaza-2-oxophenoxazine 
• 1188523-06-9 3-(2'-fluoro-2'-deoxy-β-D-ribofuranosyl)-9-(2-N-benzylcarbamyl-ethoxy)-1,3-diaza-2-oxophenoxazine 
• 1188523-02-5 5-bromo-3',5'-diacetyl-N₄-(2,6-dihydroxyphenyl)-2'-fluoro-2'-deoxycytidine 
• 1188522-96-4 5-bromo-3',5 '-diacetyl-N₄-(2-hydroxyphenyl)-2'-fluoro-2'-deoxycytidine 
• 55612-21-0 1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione 
• 1188522-91-9 5-bromo-3',5'-diacetyl-2'-fluoro-2'-deoxyuridine 
• 56287-17-3 2'-deoxy-2'-fluorouridine 
• 10212-20-1 2'-deoxy-2'-fluorocytidine 

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