1021376-74-8

Basic information

• Product Name: C₁₉H₁₈N₄O₂S
• CAS NO: 1021376-74-8
• Molecular Weight: 366.444
• Mol File: 1021376-74-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₉H₁₈N₄O₂S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₉H₁₈N₄O₂S(1021376-74-8)
• EPA Substance Registry System: C₁₉H₁₈N₄O₂S(1021376-74-8)

Safety Data

• Hazardous Substances Data: 1021376-74-8(Hazardous Substances Data)

Upstream product

• 849585-22-4 LACTIC ACID 
• 168280-54-4 3-amino-2-phenylamino-5,6,7,8-tetrahydro-3H-benzo[4,5]thieno[2,3-d]pyrimidin-4-one 

Relevant articles and documents

Title studies on the reaction of N-(3-carbethoxy-4,5,6,7-tetrahydrobenzo[b] thien-2-yl)-N′-phenylthiourea with hydrazine hydrate (Part 1)

(Chemical Equation Presented) The reaction of N-(3-carbethoxy-4,5,6,7- tetrahydrobenzo[b]thien-2-yl)-N′-phenylthiourea (1) with hydrazine hydrate in 1-butanol afforded a mixture of compounds 2, 3 and 4. Treatment of 3 and 4 with nitrous acid gave 6 and 8 respectively, while reactions of 3 with acetylacetone gave 7. Synthesis of tetracyclic compounds 9a-f and 11 from the reactions of 3 with ethyl orthoformate or appropriate acids, acid chloride, carbon disulphide and/or ethyl chloroformate. Also its reaction with isothiocyanate derivatives gave the corresponding thiosemicarbzides 12a,b which on, refluxing in alcoholic KOH gave the unexpected tetracyclic products 14a,b. Similarly the tetracyclic compounds 16a-e and 19 were obtained by cyclization of 4 and 18 respectively.