102252-95-9Relevant articles and documents
Novel cAMP PDE III Inhibitors: 1,6-Naphthyridin-2(1H)-ones
Singh, Baldev,Lesher, George Y.,Pluncket, Kevin C.,Pagani, Edward D.,Bode, Donald C.,et al.
, p. 4858 - 4865 (1992)
Two series of medorinone (3) analogs were prepared by modifications at C(2) and C(5).The C(2)-series was prepared from 2-chloro-5-methyl-1,6-naphthyridine (4) by replacement of the chloro group with various nucleophiles.The C(5)-series was prepared from 5