1023594-62-8

Basic information

• Product Name: tert-butyl(1-(2-nitrophenyl)piperidin-4-yl)carbaMate
• Synonyms: tert-butyl(1-(2-nitrophenyl)piperidin-4-yl)carbaMate;tert-butyl N-[1-(2-nitrophenyl)piperidin-4-yl]carbaMate;[1-(2-Nitro-phenyl)-piperidin-4-yl]-carbamic acid tert-butyl ester
• CAS NO: 1023594-62-8
• Molecular Formula: C16H23N3O4
• Molecular Weight: 321.37152
• Mol File: 1023594-62-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: tert-butyl(1-(2-nitrophenyl)piperidin-4-yl)carbaMate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl(1-(2-nitrophenyl)piperidin-4-yl)carbaMate(1023594-62-8)
• EPA Substance Registry System: tert-butyl(1-(2-nitrophenyl)piperidin-4-yl)carbaMate(1023594-62-8)

Safety Data

• Hazardous Substances Data: 1023594-62-8(Hazardous Substances Data)

Usage

Uses

tert-Butyl (1-(2-nitrophenyl)piperidin-4-yl)carbamate is used as a reactant in the preparation of heteroaryl amides as PIM kinase inhibitors for treating cancer.

Relevant articles and documents

PIM KINASE INHIBITORS AND METHODS OF THEIR USE

New compounds, compositions and methods of inhibition of kinase activity associated with tumorigenesis in a human or animal subject are provided. In certain embodiments, the compounds and compositions are effective to inhibit the activity of at least one serine/threonine kinase or receptor tyrosine kinase. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a serine/threonine kinase- or receptor tyrosine kinase- mediated disorder, such as cancer.