1026013-15-9 Usage
Description
3-Oxo-4-aza-11a-methoxy-5α-αndrost-1-ene-17β-carboxylic Acid Methyl Ester is an organic compound that serves as an intermediate in the synthesis of Finasteride, a pharmaceutical drug. It is characterized by its unique molecular structure, which includes a 3-oxo-4-aza steroidal framework and a methoxy group at the 11α position. 3-Oxo-4-aza-11a-Methoxy-5α-αndrost-1-ene-17β-carboxylic Acid Methyl Ester plays a crucial role in the development of medications targeting androgen-related conditions.
Uses
Used in Pharmaceutical Industry:
3-Oxo-4-aza-11a-methoxy-5α-αndrost-1-ene-17β-carboxylic Acid Methyl Ester is used as a key intermediate in the synthesis of Finasteride (F342000) for the inhibition of 5α-reductase enzyme activity. This enzyme is responsible for converting testosterone to the more potent androgen, 5α-dihydrotestosterone (DHT). By inhibiting 5α-reductase, Finasteride helps in managing conditions such as benign prostatic hyperplasia (BPH) and androgenetic alopecia (male pattern baldness), where excessive DHT levels contribute to the progression of the disease.
In the synthesis process, 3-Oxo-4-aza-11a-methoxy-5α-αndrost-1-ene-17β-carboxylic Acid Methyl Ester undergoes various chemical reactions to form Finasteride, which is then formulated into pharmaceutical products for medical use. The development of this intermediate has been instrumental in advancing the treatment options for androgen-related disorders, offering patients a more targeted and effective approach to managing their conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 1026013-15-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,6,0,1 and 3 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1026013-15:
(9*1)+(8*0)+(7*2)+(6*6)+(5*0)+(4*1)+(3*3)+(2*1)+(1*5)=79
79 % 10 = 9
So 1026013-15-9 is a valid CAS Registry Number.
