1026095-29-3Relevant articles and documents
CRYSTALLINE FORMS OF PREGABALIN
-
Page/Page column 22, (2008/12/05)
The invention relates to crystalline form of Pregabalin and their process of preparation. The invention also relates to a process for preparing 2-carbethoxy-5- methylhex-2-enoic acid ethyl ester, an important intermediate for synthesis of crystalline Pregabalin, having less than about, 1-2% 2-carbethoxy-5-methylhex-3-enoic acid ethyl ester. Moreover, the present invention provides industrially applicable process for recovery of chiral reagent used for resolution of the (±)-Pregabalin; thereby to provide cost effective and economical process for preparation of Pregabalin.