1027255-35-1Relevant articles and documents
Discovery of 2-(α-methylbenzylamino) pyrazines as potent Type II inhibitors of FMS
Burns, Christopher J.,Harte, Michael F.,Bu, Xianyong,Fantino, Emmanuelle,Giarrusso, Marilena,Joffe, Max,Kurek, Margarita,Legge, Fiona S.,Razzino, Pasquale,Su, Stephen,Treutlein, Herbert,Wan, Soo San,Zeng, Jun,Wilks, Andrew F.
, p. 1206 - 1209 (2009)
A series of 2-(α-methylbenzylamino) pyrazines have shown to be potent inhibitors of the FMS tyrosine receptor kinase. Details of SAR studies, modeling and synthesis of compounds within this series are reported.
