1027385-33-6

Basic information

• Product Name: tert-butyl [(2R,3S,5R)-2-(2,5-difluorophenyl)-5-(7H-pyrrolo[3',4':3,4]pyrazolo[1,5-b][1,2,4]triazin-8(9H)-yl)tetrahydro-2H-pyran-3-yl]carbamate
• Synonyms: tert-butyl [(2R,3S,5R)-2-(2,5-difluorophenyl)-5-(7H-pyrrolo[3',4':3,4]pyrazolo[1,5-b][1,2,4]triazin-8(9H)-yl)tetrahydro-2H-pyran-3-yl]carbamate
• CAS NO: 1027385-33-6
• Molecular Weight: 472.495
• Mol File: 1027385-33-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: tert-butyl [(2R,3S,5R)-2-(2,5-difluorophenyl)-5-(7H-pyrrolo[3',4':3,4]pyrazolo[1,5-b][1,2,4]triazin-8(9H)-yl)tetrahydro-2H-pyran-3-yl]carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl [(2R,3S,5R)-2-(2,5-difluorophenyl)-5-(7H-pyrrolo[3',4':3,4]pyrazolo[1,5-b][1,2,4]triazin-8(9H)-yl)tetrahydro-2H-pyran-3-yl]carbamate(1027385-33-6)
• EPA Substance Registry System: tert-butyl [(2R,3S,5R)-2-(2,5-difluorophenyl)-5-(7H-pyrrolo[3',4':3,4]pyrazolo[1,5-b][1,2,4]triazin-8(9H)-yl)tetrahydro-2H-pyran-3-yl]carbamate(1027385-33-6)

Safety Data

• Hazardous Substances Data: 1027385-33-6(Hazardous Substances Data)

Upstream product

• 1027385-25-6 tert-butyl 7H-pyrrolo[3',4':3,4]pyrazolo[1,5-b][1,2,4]triazine-8(9H)-carboxylate 
• 175463-32-8 3-cyano-4-oxopyrrolidine-1-carboxylic acid tert-butyl ester 
• 398491-59-3 3-amino-2,6-dihydro-4H-pyrrolo[3,4-c]pyrazole-5-carboxylic acid tert-butyl ester 
• 951127-25-6 N-[(2R,3S)-2-(2,5-difluorophenyl)tetrahydro-5-oxo-2H-pyran-3-yl]carbamic acid 1,1-dimethylethyl ester 
• 1027385-26-7 8,9-dihydro-7H-pyrrolo[3',4':3,4]pyrazolo[1,5-b][1,2,4]triazine 

Relevant articles and documents

The discovery of novel 5,6,5- and 5,5,6-tricyclic pyrrolidines as potent and selective DPP-4 inhibitors

Novel potent and selective 5,6,5- and 5,5,6-tricyclic pyrrolidine dipeptidyl peptidase IV (DPP-4) inhibitors were identified. Structure-activity relationship (SAR) efforts focused on improving the intrinsic DPP-4 inhibition potency, increasing protease se