1028342-21-3Relevant articles and documents
Enantioselective 1,3-dipolar cycloaddition of nitrones with ethyl vinyl ether: The difference between Bronsted and Lewis acid catalysis
Jiao, Peng,Nakashima, Daisuke,Yamamoto, Hisashi
, p. 2411 - 2413 (2008/12/23)
(Chemical Equation Presented) Bronsted and Lewis face off: A new chiral N-triflyl phosphoramide is used for asymmetric 1,3-dipolar cycloaddition of diaryl nitrones to ethyl vinyl ether to give the endo products in up to 93% ee (see scheme; Tf = trifluoromethanesulfonyl; Ad = adamantyl). The structure of the chiral phosphoramide was confirmed by X-ray crystallographic analysis.