10285-07-1 Usage
Description
LYCOPSAMINE is a primary reference substance with assigned absolute purity, which is an amorphous pyrrolizidine alkaloid isolated from various plant sources such as Arnsinckia hispida, A. intermedia, and A. lycopsoides. It is dextrorotatory and has alkaline hydrolysis properties, yielding retronecine and viridifloric acid.
Uses
Used in Toxicological Research:
LYCOPSAMINE is used as a hepatotoxin and tumorigen for studying the effects of pyrrolizidine alkaloid-containing plants on livestock, wildlife, and humans. It helps in understanding the biological biomarker of pyrrolizidine alkaloid-induced liver tumor formation through pyrrolizidine Alkaloid-Derived DNA Adducts.
References
Cu1venor, Smith., Austral. 1. Chern., 19, 1955 (1966)
Check Digit Verification of cas no
The CAS Registry Mumber 10285-07-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,2,8 and 5 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 10285-07:
(7*1)+(6*0)+(5*2)+(4*8)+(3*5)+(2*0)+(1*7)=71
71 % 10 = 1
So 10285-07-1 is a valid CAS Registry Number.
InChI:InChI=1/C15H25NO5/c1-9(2)15(20,10(3)17)14(19)21-8-11-4-6-16-7-5-12(18)13(11)16/h4,9-10,12-13,17-18,20H,5-8H2,1-3H3/t10-,12+,13+,15-/m0/s1
10285-07-1Relevant articles and documents
Ideamine N-Oxides: Pyrrolizidine Alkaloids Sequestered by the Danaine Butterfly, Idea leuconoe
Nishida, Ritsuo,Kim, Chul-Sa,Fukami, Hiroshi,Irie, Ryozo
, p. 1787 - 1792 (2007/10/02)
Two new pyrrolizidine alkaloids, ideamines A and B, together with other analogs (lycopsamine and parsonsine) were isolated in the N-oxide forms from adult bodies of the Apocynaceae-feeding danaine butterfly, Idea leuconoe.Ideamine A was characterized as a homolog of lycopsamine, in which the viridifloric acid moiety was replaced by a 2-ethyl-2,3-dihydroxybutanoic moiety.Likewise, ideamine B was identified as a nor-derivative of parsonsine, in which the trachelanthic acid moiety was replaced by a 2-ethyl-2,3-dihydroxybutanoic moiety diastereomeric to the necic acid from ideamine A.
Unusual macrocyclic pyrrolizidine alkaloids from Parsonsia heterophylla A. Cunn and Parsonsia spiralis Wall (Apocynaceae)
Edgar,Eggers,Jones,Russell
, p. 2657 - 2660 (2007/10/02)
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