103499-21-4

Basic information

• Product Name: 3-BENZYL-5-(BROMOMETHYL)-1,2,4-OXADIAZOLE
• Synonyms: 3-BENZYL-5-(BROMOMETHYL)-1,2,4-OXADIAZOLE
• CAS NO: 103499-21-4
• Molecular Formula: C₁₀H₉BrN₂O
• Molecular Weight: 253.11
• Mol File: 103499-21-4.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-BENZYL-5-(BROMOMETHYL)-1,2,4-OXADIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BENZYL-5-(BROMOMETHYL)-1,2,4-OXADIAZOLE(103499-21-4)
• EPA Substance Registry System: 3-BENZYL-5-(BROMOMETHYL)-1,2,4-OXADIAZOLE(103499-21-4)

Safety Data

• Hazardous Substances Data: 103499-21-4(Hazardous Substances Data)

Upstream product

• 22118-09-8 2-bromoacetyl chloride 
• 19227-11-3 N'-hydroxy-2-phenylethanimidamide 
• 598-21-0 2-Bromoacetyl bromide 
• 140-29-4 phenylacetonitrile 

Relevant articles and documents

Design, semisynthesis and cytotoxic activity of novel ester derivatives of betulinic acid-1,2,4 oxadiazoles

Taking into consideration of the biological activity of betulinic acid derivatives containing a oxadiazole ring, the semisynthetic betulinic acid-1,2,4-oxadiazole esters (14–25) were synthesized starting from betulinic acid (1) and 5-(bromomethyl)-3-aryl-1,2,4-oxadiazoles (2–13) and final compounds were tested for cytotoxic activity on three human cancer cell lines in vitro. All tested compounds showed good cytotoxic activity. The structures of synthesized compounds are established based on infrared (IR), nuclear magnetic resonance (NMR), and mass spectrometry.