10354-56-0

Basic information

• Product Name: N-cyclohexylpyridine-3-carboxamide
• Synonyms: 3-pyridinecarboxamide, N-cyclohexyl-; N-Cyclohexylnicotinamide
• CAS NO: 10354-56-0
• Molecular Formula: C₁₂H₁₆N₂O
• Molecular Weight: 204.2682
• Mol File: 10354-56-0.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 416.5°C at 760 mmHg
• Flash Point: 205.7°C
• Density: 1.1g/cm³
• Vapor Pressure: 3.8E-07mmHg at 25°C
• Refractive Index: 1.548
• CAS DataBase Reference: N-cyclohexylpyridine-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-cyclohexylpyridine-3-carboxamide(10354-56-0)
• EPA Substance Registry System: N-cyclohexylpyridine-3-carboxamide(10354-56-0)

Safety Data

• Hazardous Substances Data: 10354-56-0(Hazardous Substances Data)

Upstream product

• 110-82-7 cyclohexane 
• 98-92-0 nicotinamide 
• 108-85-0 1-bromocyclohexane 
• 3173-53-3 Cyclohexyl isocyanate 
• 108-91-8 cyclohexylamine 
• 626-62-0 Cyclohexyl iodide 
• 10400-19-8 3-pyridinecarbonyl chloride 
• 191799-02-7 N-cyclohexyl-N-tert-butylnicotinamide 
• 51609-06-4 N-(tert-butyl)cyclohexanamine 

Downstream Products

• 1248342-75-7 fac-[Re(CO)3(2,2-bipyridine)(cyclohexylnicotinate][OTf] 
• 124179-33-5 3,3'-bis-cyclohexylcarbamoyl-1,1'-ethanediyl-bis-pyridinium; dibromide 

Relevant articles and documents

Synthesis and characterization of Pd(II)–vitamin B6 complex supported on magnetic nanoparticle as an efficient and recyclable catalyst system for C–N cross coupling of amides in deep eutectic solvents

Vitamin B6–Pd(II) immobilized onto magnetic nanoparticles have been successfully prepared and applied for C–Xcross-coupling reactions with aryl halides in green deep eutectic solvents. The results prove that the Fe3O4@vitamin B6–Pd(II) magnetic nanoparticles show high catalyst activity and good stability. It was also revealed that this complex can be recycled up to five times without any significant loss in catalytic activity.

Nickel-catalyzed reductive amidation of aryl-triazine ethers

The reaction of activated phenolic compounds, 2,4,6-triaryloxy-1,3,5-triazine (aryl-triazine ethers), with various isocyanates or carbodiimides in the presence of a nickel pre-catalyst resulted in the synthesis of aryl amides in good to excellent yields.

Benzoic acid-catalyzed transamidation reactions of carboxamides, phthalimide, ureas and thioamide with amines

An efficient and simple method for the transamidation of carboxamides, phthalimide, ureas and thioamide with amines catalyzed by commercially available benzoic acid under metal-free conditions is described. Furthermore, to the best of our knowledge, this is the first report about the transamidation of an aromatic thioamide with amines.