103656-73-1

Basic information

• Product Name: Phenol, 2-(5-phenyl-2-oxazolyl)-
• CAS NO: 103656-73-1
• Molecular Formula: C15H11NO2
• Molecular Weight: 237.258
• Mol File: 103656-73-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Phenol, 2-(5-phenyl-2-oxazolyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2-(5-phenyl-2-oxazolyl)-(103656-73-1)
• EPA Substance Registry System: Phenol, 2-(5-phenyl-2-oxazolyl)-(103656-73-1)

Safety Data

• Hazardous Substances Data: 103656-73-1(Hazardous Substances Data)

Upstream product

• 4846-21-3 O-phenylhydroxylamine 
• 108-95-2 phenol 
• 1006-68-4 5-phenyloxazole 
• 5661-50-7 N-(phenoxy)acetamide 
• 98-80-6 phenylboronic acid 
• 64908-64-1 2-phenoxyisoindol-1,3-dione 
• 5468-37-1 2-aminoacetophenone hydrochloride 
• 90-02-8 salicylaldehyde 
• 17064-26-5 2-(2-methoxyphenyl)-5-phenyl-1,3-oxazole 

Relevant articles and documents

Bipyridine-Type Bidentate Auxiliary-Enabled Copper-Mediated ?C-H/C-H Biaryl Coupling of Phenols and 1,3-Azoles

A copper-mediated dehydrogenative C-H/C-H biaryl coupling of phenols and 1,3-azoles has been developed. The key to its success is the introduction of a bipyridine-type bidentate auxiliary, 4,4′-di(tert-butyl)-2,2′-bipyridine, on the phenol oxygen, which is readily prepared and easily attachable, detachable, and recyclable. The reaction proceeds smoothly in the presence of copper salt alone to form the corresponding phenol-azole heterobiaryls, which are prevalent motifs in functional molecules such as excited-state intramolecular proton transfer materials.

Simple and efficient preparation of 2,5-disubstituted oxazoles via a metal-free-catalyzed cascade cyclization

A practical and simple synthesis of 2,5-disubstituted oxazoles was developed via an iodine-catalyzed tandem oxidative cyclization. A wide range of common commercial aromatic aldehydes can be used as reaction substrates, which displayed excellent functional group compatibility in this reaction.