103802-43-3Relevant articles and documents
Three Sequential C-N Bond Formations: Tert-Butyl Nitrite as a N1 Synthon in a Three Component Reaction Leading to Imidazo[1,2-a]quinolines and Imidazo[2,1-a]isoquinolines
Sau, Prasenjit,Rakshit, Amitava,Modi, Anju,Behera, Ahalya,Patel, Bhisma K.
, p. 1056 - 1064 (2018)
tert-Butyl nitrite serves the dual role of an oxidant as well as a N1 synthon in a multicomponent reaction involving quinolines, isoquinolines, and styrenes. Herein, two sp2 C-H functionalizations of styrenes and one sp2 C-H functionalization of quinolines and isoquinolines lead to the formation of fused quinolines and isoquinolines via three sequential C-N bond formations.
Imidazo(1,2-a)quinoline derivatives useful as anxiolytic agents
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, (2008/06/13)
Compounds which are imidazo[1,2-a]quinoline derivatives of general formula (I) STR1 in which X is hydrogen, halogen, (C1-4)alkyl, (C1-4)alkoxy, (C1-4) alkylthio, methylsulphonyl, amino, (C1-4)alkylamino, di-(C1-4)alkylamino, nitro or trifluoromethyl, Y is hydrogen, halogen or methyl in position 6, 7 or 8, R1 and R2, which may be the same or different, are hydrogen or (C1-6) alkyl, or R1 and R2 together form a tetramethylene, pentamethylene, 3-methyl-3-azapentamethylene, 3-ethoxycarbonyl-3-azapentamethylene group, and A and B both are hydrogen or together form a carbon-carbon bond, and their pharmacologically acceptable acid addition salts have anxiolytic, sleep-inducing, hypnotic, anticonvulsant, analgesic and anti-ulcer properties.
