103831-11-4 Usage
Description
3-Aminopyrrolidine dihydrochloride, also known as 3-pyrrolidinamine dihydrochloride, is an essential intermediate in the synthesis of tosufloxacin and other quinolone antibiotics. It is a chemical compound with a molecular structure that features a pyrrolidine ring and an amine group, which makes it a versatile reagent in various applications.
Uses
Used in Pharmaceutical Industry:
3-Aminopyrrolidine dihydrochloride is used as a key intermediate for the synthesis of tosufloxacin and other quinolone antibiotics. These antibiotics are widely used to treat bacterial infections due to their broad-spectrum activity and effectiveness against a range of pathogens.
Used in Analytical Chemistry:
3-Aminopyrrolidine dihydrochloride is used as an internal standard for the quantitative analysis of amino acids in bio-fluids. Its stable and well-defined chemical properties make it an ideal reference compound for accurate and reliable measurements in various analytical techniques.
Used in Chemical Synthesis:
(R,S) 3-Aminopyrrolidine dihydrochloride may be used in the preparation of cis-[PdCl2(pyrr)] and cis-[PtCl2(pyrr)] complexes (pyrr = (R,S)-3-aminopyrrolidine). These complexes have potential applications in various fields, including catalysis and medicinal chemistry, due to their unique structural and electronic properties.
Check Digit Verification of cas no
The CAS Registry Mumber 103831-11-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,8,3 and 1 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 103831-11:
(8*1)+(7*0)+(6*3)+(5*8)+(4*3)+(3*1)+(2*1)+(1*1)=84
84 % 10 = 4
So 103831-11-4 is a valid CAS Registry Number.
InChI:InChI=1/C4H10N2.ClH/c5-4-1-2-6-3-4;/h4,6H,1-3,5H2;1H
103831-11-4Relevant articles and documents
Process for producing 1H-3-aminopyrrolidine and derivatives thereof
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Page 14, (2008/06/13)
A process for producing 1H-3-aminopyrrolidine and derivatives thereof is disclosed. The process is especially useful for producing optically active 1H-3-aminopyrrolidine and derivatives thereof and in this case comprises reacting an optically active amino-protected aspartic anhydride represented by the formula (1) with a primary amine represented by the formula R'NH2, subjecting the reaction product to cyclodehydration to obtain an optically active 1-aralkyl-3-(protected amino)pyrrolidine-2,5-dione compound represented by the formula (2), subsequently eliminating the protective group from the 3-position amino group of the compound represented by the formula (2) to obtain an optically active 1-aralkyl-3-aminopyrrolidine-2,5-dione compound represented by the formula (3), reducing the carbonyl groups of the compound represented by the formula (3) to obtain either an optically active 1-aralkyl-3-aminopyrrolidine compound represented by the formula (4) or a salt thereof with a protonic acid, and then subjecting the compound represented by the formula (4) or the salt thereof to hydrogenolysis to obtain an optically active 1H-3-aminopyrrolidine or a protonic acid salt thereof.
1-tertiary-alkyl-substituted naphthyridine carboxylic acid antibacterial agents
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, (2008/06/13)
There are disclosed new naphthyridine- and quinoline-carboxylic acids having a 1-tertiary-alkyl substituent, compositions containing them, and their use in treating bacterial infections in warm-blooded animals. Also disclosed are novel amines and intermediates used in the preparation of the naphthyridine- and quinoline-carboxylic acids.
