1040274-54-1

Basic information

• Product Name: 2-phenyl-but-3-yne-1,2-diol
• Synonyms: 2-phenyl-but-3-yne-1,2-diol
• CAS NO: 1040274-54-1
• Molecular Weight: 162.188
• Mol File: 1040274-54-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-phenyl-but-3-yne-1,2-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-but-3-yne-1,2-diol(1040274-54-1)
• EPA Substance Registry System: 2-phenyl-but-3-yne-1,2-diol(1040274-54-1)

Safety Data

• Hazardous Substances Data: 1040274-54-1(Hazardous Substances Data)

Upstream product

• 582-24-1 1-phenyl-2-hydroxyethanone 
• 4301-14-8 acetylenemagnesium bromide 
• 1429938-88-4 2-phenyl-4-trimethylsilanyl-but-3-yne-1,2-diol 
• 100-52-7 benzaldehyde 

Downstream Products

• 13679-41-9 3-phenylfuran 
• 1174824-68-0 (R)-2-phenyl-2-((4-(trifluoromethyl)phenyl)amino)but-3-yn-1-ol 

Relevant articles and documents

Copper-Catalyzed Enantioselective Construction of Tertiary Propargylic Sulfones

Tertiary propargylic sulfones are of significant importance in organic synthesis and medicinal chemistry, but to date no general asymmetric synthesis approach has been developed. We disclose a versatile copper-catalyzed sulfonylation of propargylic cyclic carbonates using sodium sulfinates that allows the construction of propargylic sulfones featuring elusive quaternary stereocenters. This method provides the first successful example of such an enantioselective propargylic sulfonylation, features high asymmetric induction, wide functional group tolerance, and scalability, and enables attractive product diversification.

Poly(ethylene glycol) as a reaction matrix in platinum- or gold-catalyzed cycloisomerization: A mechanistic investigation

Design for diversity: A new catalytic system based on PEG-3400 and a metal salt (Pt or Au) was designed to efficiently perform a cycloisomerization reaction under microwave irradiation, which gave diverse heterocycles in good to excellent yields, after a