10409-10-6

Basic information

• Product Name: 3-hydroxy-2,3-diphenylbutanoic acid
• CAS NO: 10409-10-6
• Molecular Formula: C₁₆H₁₆O₃
• Molecular Weight: 256.2964
• Mol File: 10409-10-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 395.2°C at 760 mmHg
• Flash Point: 207°C
• Density: 1.222g/cm³
• Vapor Pressure: 5.91E-07mmHg at 25°C
• Refractive Index: 1.605
• CAS DataBase Reference: 3-hydroxy-2,3-diphenylbutanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-hydroxy-2,3-diphenylbutanoic acid(10409-10-6)
• EPA Substance Registry System: 3-hydroxy-2,3-diphenylbutanoic acid(10409-10-6)

Safety Data

• Hazardous Substances Data: 10409-10-6(Hazardous Substances Data)

Upstream product

• 4870-65-9 2-bromophenylacetic acid 
• 98-86-2 acetophenone 
• 95777-19-8 phenylacetic acid magnesium enediolate 

Downstream Products

• 103-82-2 phenylacetic acid 
• 98-86-2 acetophenone 
• 42909-07-9 cis-3,4-Diphenyl-pent-3-en-2-on 
• 42909-06-8 trans-3,4-Diphenyl-pent-3-en-2-on 
• 58929-04-7 3-hydroxy-2,3-diphenyl-butyric acid ethyl ester 
• 93158-20-4 2,3-dicyclohexyl-3-hydroxy-butyric acid 
• 10408-73-8 3-methyl-2-phenyl-inden-1-one 

Relevant articles and documents

Kinetics and Mechanism of the Ivanov Reaction: Reaction of Aldehydes and Ketones with Phenylacetic Acit Magnesium Enediolate

Stopped-flow kinetics of the reaction between aldehydes or ketones and the magnesium enediolate of phenylacetic acid in THF are second order at enediolate concentrations -3 M.At concentrations of 10-3 - 3*10-2 M, the formation of a bis(enediolate) requires a more complex kinetic equation.Second-order rate constans are reported for the reaction of the enediolate with a number of aldehydes and ketones at 25 deg C.Entropies of activation for cyclohexanone, benzaldehyde, 2-methylpropanal, and 2,2-dimethylpropanal are positive, and enthalpy-entropy compensation is observed.Ef fects of cycloalkanone ring size and benzaldehyde substituents are small and are ascribable to a transition state with a very small C-C bond order.A two-step mechanism is proposed, with preequilibrium formation of a coordination intermediate which, in some cases, is accompanied by a change in the magnesium coordination number.Effects of alkyl groups on aldehyde and ketone reactivity stem mainly from steric desolvation.