1041026-64-5

Basic information

• Product Name: 2,6-Diazaspiro[3.3]heptane, 2-[(4-Methylphenyl)sulfonyl]-6-(phenylMethyl)-
• Synonyms: 2,6-Diazaspiro[3.3]heptane, 2-[(4-Methylphenyl)sulfonyl]-6-(phenylMethyl)-;2-benzyl-6-tosyl-2,6-diazaspiro[3.3]heptane
• CAS NO: 1041026-64-5
• Molecular Formula: C₁₉H₂₂N₂O₂S
• Molecular Weight: 342.45518
• Mol File: 1041026-64-5.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,6-Diazaspiro[3.3]heptane, 2-[(4-Methylphenyl)sulfonyl]-6-(phenylMethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Diazaspiro[3.3]heptane, 2-[(4-Methylphenyl)sulfonyl]-6-(phenylMethyl)-(1041026-64-5)
• EPA Substance Registry System: 2,6-Diazaspiro[3.3]heptane, 2-[(4-Methylphenyl)sulfonyl]-6-(phenylMethyl)-(1041026-64-5)

Safety Data

• Hazardous Substances Data: 1041026-64-5(Hazardous Substances Data)

Usage

General Description

2,6-Diazaspiro[3.3]heptane, 2-[(4-Methylphenyl)sulfonyl]-6-(phenylMethyl)- is a chemical compound that belongs to the class of spiro compounds, which are characterized by a unique structure containing two or more rings that share a single atom. This specific compound contains a spiro ring system with a diazaspiro[3.3]heptane structure, as well as substituents attached to it. These substituents include a sulfonyl group attached to the 2-position of the spiro ring, and a phenylmethyl group attached to the 6-position. The compound also contains a methyl group attached to the phenyl ring. This chemical's unique structure and functional groups give it potential application in pharmaceutical and organic synthesis processes.

Upstream product

• 70-55-3 toluene-4-sulfonamide 
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• 1041026-61-2 3,3-bis(bromomethyl)-1-(p-toluenesulfonyl)azetidine 
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• 1522-92-5 2,2-bis(bromomethyl)-3-bromo-propan-1-ol 

Downstream Products

• 1333960-25-0 C₁₂H₁₆N₂O₂S 
• 1041026-67-8 tert-butyl 6-(p-toluenesulfonyl)-2,6-diazaspiro[3.3]heptane-2-carboxylate 
• 1041026-71-4 2,6-diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate 

Relevant articles and documents

1-azaspirocycle compound, and preparation method and applications thereof

The invention discloses a 1-azaspirocycle compound, and preparation method and applications thereof, and belongs to the field of pharmaceutical chemistry. The 1-azaspirocycle compound with a structurerepresented by formula I, or a pharmaceutically acceptable salt or a stereisomer or a solvate or a prodrug thereof is capable of realzing combination with Autotaxin, can be taken as an Autotaxin inhibitor, and can be used for prevention and treatment of diseases with Autotaxin expression increasing pathological characteristics such as cancer and fibrosis diseases especially pulmonary fibrosis andhepatic fibrosis, metabolic diseases, myelodysplastic syndrome, cardiovascular diseases, autoimmune diseases, inflammation, neurological diseasses, or pain. Compared with single component inhibitors,the 1-azaspirocycle compound and the derivatives possesses following advantages: blocking and interfacing at the upsteam of a plurality of key signal channels are realized, tumor cell growth and transfer are relieved or dalyed, early caused drug resistance is avoided, and novel means are provided for treatment of tumor cells.

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