104405-59-6 Usage
General Description
6-BROMO-1,2,4-TRIAZINE-3,5-DIAMINE is a chemical compound with the molecular formula C3H4BrN5. It is a brominated triazine derivative that is commonly used in the synthesis of pharmaceuticals and agrochemicals. The compound is known for its potent biological activities and is often used as a building block in the preparation of various biologically active molecules. It is also used in the manufacturing of dyes, pigments, and other organic compounds. 6-BROMO-1,2,4-TRIAZINE-3,5-DIAMINE has a wide range of applications in the chemical industry and is a valuable intermediate in the synthesis of various organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 104405-59-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,4,4,0 and 5 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 104405-59:
(8*1)+(7*0)+(6*4)+(5*4)+(4*0)+(3*5)+(2*5)+(1*9)=86
86 % 10 = 6
So 104405-59-6 is a valid CAS Registry Number.
104405-59-6Relevant articles and documents
Improved method for synthetizing lamotrigine
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Paragraph 0046; 0047; 0048, (2018/07/06)
The invention discloses an improved method for synthetizing lamotrigine. The method comprises the following steps: step I, carrying out helogenating reaction through 3-amino-1,2,4-triazine (I) and a halogenating reagent in the presence of an organic solvent to obtain 3-amino 6-halogeno-1,2,4-triazine (II); step II, carrying out amination reaction of a compound II to prepare 3,5-diamino 6-halogeno-1,2,4-triazine (compound III); and step III, carrying out suzuki coupling reaction through the compound III and 2,3-dichlorobenzene boric acid derivative in the solvent under catalysis of palladium/[N,N] pyridine amidino ligand/alkali to prepare lamotrigine (IV). Through the method, metal cyanide is not used; meanwhile, the method is high in reaction selectivity and high in reaction yield.
Liquid Ammonia/Potassium Permanganate, A Useful Reagent in the Chichibabin Amination of 1,2,4-Triazines
Rykowski, A.,Plas, H. C. van der
, p. 884 - 886 (2007/10/02)
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