1044695-85-3

Basic information

• Product Name: 1-[4-(tert-butyl)phenyl]ethane-1,2-diol
• Synonyms: 1-[4-(tert-butyl)phenyl]ethane-1,2-diol
• CAS NO: 1044695-85-3
• Molecular Weight: 194.274
• Mol File: 1044695-85-3.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 1-[4-(tert-butyl)phenyl]ethane-1,2-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[4-(tert-butyl)phenyl]ethane-1,2-diol(1044695-85-3)
• EPA Substance Registry System: 1-[4-(tert-butyl)phenyl]ethane-1,2-diol(1044695-85-3)

Safety Data

• Hazardous Substances Data: 1044695-85-3(Hazardous Substances Data)

Upstream product

• 1746-23-2 4-tert-Butylstyrene 
• 2783-28-0 4-tert-butylphenylethylene oxide 
• 50-00-0 formaldehyd 
• 939-97-9 4-tert-Butylbenzaldehyde 
• 5406-86-0 2-(4-tert-butylphenyl)ethanol 

Downstream Products

• 98-73-7 4-(1,1-dimethylethyl)benzoic acid 
• 92-92-2 biphenyl-4-carboxylic acid 
• 1044696-02-7 1-tert-butyldimethylsilyloxy-2-hydroxy-2-(4-tertbutylphenyl)ethane 
• 1044695-89-7 2-tert-butyl-4-chloro-5-(2-tert-butyldimethylsilyloxy-1-(4-tert-butylphenyl)-1-ethyl)oxy-3(2H)-pyridazinone 
• 1044696-29-8 2-tert-butyl-4-chloro-5-(2-p-toluene-sulfonyloxy-1-(4-tert-butylphenyl)-1-ethyl)oxy-3(2H)-pyridazinone 
• 1044695-70-6 2-tert-butyl-4-chloro-5-(2-fluoro-1-(4-tert-butylphenyl)-1-ethyl)oxy-3(2H)-pyridazinone 
• 1186389-16-1 2-tert-butyl-4-chloro-5-(2-[’8F]-fluoro-1-(4-tert-butylphenyl)-1-ethyl)oxy-3(2H)-pyridazinone 
• 299165-27-8 2-(4-tert-butylphenyl)glycine 
• 7099-90-3 2-(4-(tert-butyl)phenyl)-2-oxoacetic acid 
• 939-97-9 4-tert-Butylbenzaldehyde 
• 1375102-71-8 C₁₇H₂₆O₃ 
• 1375102-75-2 C₁₈H₂₅NO₂S 
• 1375102-73-0 C₁₇H₂₅N₃O₂ 
• 1375102-78-5 C₂₆H₃₆FN₃O₄S₂ 

Relevant articles and documents

Catalytic Diastereo- and Enantioconvergent Synthesis of Vicinal Diamines from Diols through Borrowing Hydrogen

We present herein an unprecedented diastereoconvergent synthesis of vicinal diamines from diols through an economical, redox-neutral process. Under cooperative ruthenium and Lewis acid catalysis, readily available anilines and 1,2-diols (as a mixture of diastereomers) couple to forge two C?N bonds in an efficient and diastereoselective fashion. By identifying an effective chiral iridium/phosphoric acid co-catalyzed procedure, the first enantioconvergent double amination of racemic 1,2-diols has also been achieved, resulting in a practical access to highly valuable enantioenriched vicinal diamines.

Iodine-Initiated Dioxygenation of Aryl Alkenes Using tert-Butylhydroperoxides and Water: A Route to Vicinal Diols and Bisperoxides

An environment-friendly and efficient dioxygenation of aryl alkenes for the construction of vicinal diols has been developed in water with iodine as the catalyst and tert-butylhydroperoxides (TBHPs) as the oxidant. The protocol was efficient, sustainable, and operationally simple. Detailed mechanistic studies indicated that one of the hydroxyl groups is derived from water and the other one is derived from TBHP. Additionally, the bisperoxides could be obtained in good yields with iodine as the catalyst, Na2CO3 as the additive, and propylene carbonate as the solvent, instead.

Synthesis of Unprotected 2-Arylglycines by Transamination of Arylglyoxylic Acids with 2-(2-Chlorophenyl)glycine

The transamination of α-keto acids with 2-phenylglycine is an effective methodology for directly synthesizing unprotected α-amino acids. However, the synthesis of 2-arylglycines by transamination is problematic because the corresponding products, 2-arylglycines, transaminate the starting arylglyoxylic acids. Herein, we demonstrate the use of commercially available l-2-(2-chlorophenyl)glycine as the nitrogen source in the transamination of arylglyoxylic acids, producing the corresponding 2-arylglycines without interference from the undesired self-transamination process.