104883-11-6

Basic information

• Product Name: 2-methylallyl (3RS,4SR)-trans-<4-allyl-3-(2-hydroxypropan-2-yl)-2-oxoazetidin-1-yl>triphenylphosphoranylideneacetate
• CAS NO: 104883-11-6
• Molecular Weight: 541.627
• Mol File: 104883-11-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-methylallyl (3RS,4SR)-trans-<4-allyl-3-(2-hydroxypropan-2-yl)-2-oxoazetidin-1-yl>triphenylphosphoranylideneacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methylallyl (3RS,4SR)-trans-<4-allyl-3-(2-hydroxypropan-2-yl)-2-oxoazetidin-1-yl>triphenylphosphoranylideneacetate(104883-11-6)
• EPA Substance Registry System: 2-methylallyl (3RS,4SR)-trans-<4-allyl-3-(2-hydroxypropan-2-yl)-2-oxoazetidin-1-yl>triphenylphosphoranylideneacetate(104883-11-6)

Safety Data

• Hazardous Substances Data: 104883-11-6(Hazardous Substances Data)

Upstream product

• 104883-08-1 (2-Allyl-4-oxo-azetidin-1-yl)-chloro-acetic acid 2-methyl-allyl ester 
• 104883-06-9 2-methylallyl (4-allyl-2-oxoazetidin-1-yl)-1-hydroxyacetate 
• 68485-52-9 4-allylazetidin-2-one 
• 104883-10-5 2-methylallyl (4-allyl-2-oxoazetidin-1-yl)triphenylphosphoranylideneacetate 
• 67-64-1 acetone 

Downstream Products

• 104883-15-0 p-nitrobenzyl (5RS,6SR)-6-(2-hydroxypropan-2-yl)-7-oxo-1-azabicyclo<3.2.0>hept-2-ene-2-carboxylate 
• 104883-15-0 p-nitrobenzyl (5RS,6RS)-6-(2-hydroxypropan-2-yl)-7-oxo-1-azabicyclo<3.2.0>hept-2-ene-2-carboxylate 

Relevant articles and documents

Olivanic Acid Analogues. Part 2. Total Synthesis of Some C(6)-Substituted 7-Oxo-1-azabicyclohept-2-ene-2-carboxylates

A number of 6-substituted 7-oxo-1-azabicyclohept-2-ene-2-carboxylates related to the olivanic acids were prepared from the phosphorane (32).Generation of the anion α to the azetidin-2-one carbonyl group, followed by reaction with electrophiles and intramolecular cyclisation using the Wittig procedure gave the bicyclic products; in all cases the thermodynamically favoured trans-stereochemisty about the azetidinone ring predominated.In contrast, some less readily available cis-substituted analogues were obtained from the cyclohexa-1,4-diene derived phosphorane (61).The synthetic utility of a masked acetonyl ester group for preparing the free acids of these azabicycloheptene ring systems is described.