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1049809-51-9

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1049809-51-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1049809-51-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,9,8,0 and 9 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1049809-51:
(9*1)+(8*0)+(7*4)+(6*9)+(5*8)+(4*0)+(3*9)+(2*5)+(1*1)=169
169 % 10 = 9
So 1049809-51-9 is a valid CAS Registry Number.

1049809-51-9Downstream Products

1049809-51-9Relevant articles and documents

Practical synthesis of a cathepsin S Inhibitor: Route identification, purification strategies, and serendipitous discovery of a crystalline salt form

Deng, Xiaoliu,Liang, Jimmy T.,Peterson, Matthew,Rynberg, Raymond,Cheung, Eugene,Mani, Neelakandha S.

experimental part, p. 1940 - 1947 (2010/05/18)

Chemical Equation Presented A redox economical strategy resulted in a concise, modular synthesis of compound 1, a potent Cathepsin S inhibitor. Starting from three building blocks, crude drug substance was prepared, in a two-step sequence in high yield. Efficient purification of the crude drug substance was accomplished via the formation of an unusual monoethyl oxalate salt.

Pyrazole-based cathepsin S inhibitors with arylalkynes as P1 binding elements

Ameriks, Michael K.,Axe, Frank U.,Bembenek, Scott D.,Edwards, James P.,Gu, Yin,Karlsson, Lars,Randal, Mike,Sun, Siquan,Thurmond, Robin L.,Zhu, Jian

scheme or table, p. 6131 - 6134 (2010/06/13)

A crystal structure of 1 bound to a Cys25Ser mutant of cathepsin S helped to elucidate the binding mode of a previously disclosed series of pyrazole-based CatS inhibitors and facilitated the design of a new class of arylalkyne analogs. Optimization of the

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