105118-17-0Relevant articles and documents
Total synthesis of both enantiomers of trans-2,3-cis-3,4-dihydroxyproline
Zanardi, Franca,Battistini, Lucia,Nespi, Marika,Rassu, Gloria,Spanu, Pietro,Cornia, Mara,Casiraghi, Giovanni
, p. 1167 - 1180 (1996)
Both enantiomers of trans-2,3-cis-3,4-dihydroxyproline, 4 and 5, have been stereoselectively synthesized from 2,3-O-isopropylidene-D-glyceraldehyde 1, by taking advantage of a divergent and parallel synthetic strategy, utilizing N-(tert-butoxycarbonyl)-2-(tert-butyldimethylsiloxy)pyrrole (TBSOP) as the common four-carbon synthon.
Asymmetric Synthesis of d -Proline, d -Pipecolic Acid, (2 R,3 S,4 R)-3,4-Dihydroxyproline, and 1,4-Dideoxy-1,4-imino- d -talitol from a Common Precursor
Chattopadhyay, Shital K.,Mukherjee, Jyoti Prasad
, p. 2481 - 2488 (2015/12/26)
Methodology involving stereoselective aza-Michael addition and ring-closing metathesis as key steps has been developed for the preparation of (2R)-pipecolic acid, (2R)-proline, (2R,3S,4R)-3,4-dihydroxyproline, and the known glycosidase inhibiting azasugar 1,4-dideoxy-1,4-imino-d-talitol from a common starting material namely (R)-cyclohexylideneglyceraldehyde in good overall yields.
Efficient synthesis of a new aminoazasugar and dihydroxyprolines from an endocyclic enecarbamate
Pohlit, Adrian M.,Correia, Carlos Roque D.
, p. 2321 - 2325 (2007/10/03)
A novel procedure for the synthesis of trans-2,3-(2-aminomethyl)-cis-3,4-dihydroxypyrrolidine (a new aminoazasugar) and cis-2,3- and trans-2,3-cis-3,4-dihydroxyprolines is presented. Starting from the known endocyclic enecarbamate 1-carbobenzyloxy-2-pyrro
