10547-61-2

Basic information

• Product Name: (3-CHLORO-4-METHOXYPHENYL)(PHENYL)METHANONE
• Synonyms: (3-CHLORO-4-METHOXYPHENYL)(PHENYL)METHANONE
• CAS NO: 10547-61-2
• Molecular Formula: C₁₄H₁₁ClO₂
• Molecular Weight: 246.69
• Mol File: 10547-61-2.mol
• Article Data: 5

Chemical Properties

• Melting Point: 99°C
• Appearance: /
• CAS DataBase Reference: (3-CHLORO-4-METHOXYPHENYL)(PHENYL)METHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: (3-CHLORO-4-METHOXYPHENYL)(PHENYL)METHANONE(10547-61-2)
• EPA Substance Registry System: (3-CHLORO-4-METHOXYPHENYL)(PHENYL)METHANONE(10547-61-2)

Safety Data

• Hazardous Substances Data: 10547-61-2(Hazardous Substances Data)

Usage

Preparation

Obtained by heating for 4 h a mixture of 2-chloroanisole and benzoyl chloride,in the presence of ferric chloride (70%) in the presence of aluminium chloride (81%).

Upstream product

• 611-94-9 4-Methoxybenzophenone 
• 766-51-8 2-Chloroanisole 
• 98-88-4 benzoyl chloride 
• 7446-70-0 aluminium trichloride 
• 630-20-6 1,1,1,2-tetrachoroethane 
• 77-78-1 dimethyl sulfate 
• 65-85-0 benzoic acid 
• 774-65-2 benzoic acid tert-butyl ester 

Downstream Products

• 55191-20-3 (3-chloro-4-hydroxyphenyl)(phenyl)methanone 
• 860564-09-6 3,5-dichloro-4-methoxy-benzophenone 
• 812685-01-1 2-(3-chloro-4-methoxy-phenyl)-2-phenyl-[1,3]dioxolane 
• 34183-06-7 (3,5-dichloro-4-hydroxyphenyl)(phenyl)methanone 
• 64133-84-2 2-(4-benzoyl-2-chlorophenyl)-2-phenylpropanenitrile 

Relevant articles and documents

Organic Superbase t-Bu-P4 Catalyzes Amination of Methoxy(hetero)arenes

We report that the organic superbase t-Bu-P4 efficiently catalyzes the amination of methoxy(hetero)arenes with amine nucleophiles such as aniline, indoline, and aminopyridine derivatives. This catalytic reaction is effective for the transformation of elec

Esters as acylating reagent in a Friedel-Crafts reaction: Indium tribromide catalyzed acylation of arenes using dimethylchlorosilane

(Chemical Equation Presented) The Friedel-Crafts acylation of arenes with esters by dimethylchlorosilane and 10 mol % of indium tribromide has been achieved. The key intermediate RCOOSi(Cl)Me2 is generated from alkoxy esters with the evolution of the corresponding alkanes. The scope of the alkoxy ester moiety was wide: tert-butyl, benzyl, allyl, and isopropyl esters were successful. In addition, we demonstrated the direct synthesis of the indanone intermediate 11 of salviasperanol from ester 10.

ACYLATION OF CHLOROANISOLES

In the reaction of 2-, 3-, and 4-chloroanisoles with the chlorides and anhydrides of acetic, propionic, and 4-substituted benzoic acids in the presence of 1E-3 mole of ferric chloride 35-80percent of the ketone fraction was obtained.Under the reaction con