1055303-64-4

Basic information

• Product Name: 2-(4-fluorophenyl)ethane-1-thiol
• Synonyms: 2-(4-fluorophenyl)ethane-1-thiol
• CAS NO: 1055303-64-4
• Molecular Weight: 156.224
• Mol File: 1055303-64-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(4-fluorophenyl)ethane-1-thiol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-fluorophenyl)ethane-1-thiol(1055303-64-4)
• EPA Substance Registry System: 2-(4-fluorophenyl)ethane-1-thiol(1055303-64-4)

Safety Data

• Hazardous Substances Data: 1055303-64-4(Hazardous Substances Data)

Usage

Type of compound

Thiol (contains a sulfur atom bonded to a hydrogen atom and an organic group)

Uses

Organic synthesis, building block in the production of pharmaceuticals and agrochemicals, production of perfumes and flavorings

Odor

Strong and unpleasant

Potential applications

Medicinal chemistry (interaction with biological targets, valuable tool in drug discovery and development)

Precautions

Strong odor and potential for skin and eye irritation (use with caution)

Upstream product

• 157254-77-8 C₉H₁₁FN₂S*BrH 
• 332-42-3 (2-bromoethyl)-4-fluorobenzene 
• 455267-22-8 thioacetic acid S-[2-(4-fluoro-phenyl)-ethyl] ester 

Downstream Products

• 1055303-72-4 3-[4-(tert-butyl-dimethyl-silanyloxymethyl)-phenyl]-2-[2-(4-fluoro-phenyl)-ethylsulfanyl]-propionic acid methyl ester 
• 1415676-36-6 C₁₆H₁₇FN₄O₂S 
• 1415676-58-2 C₁₆H₁₇FN₄O₃S 
• 1055303-82-6 4-[2-[2-(4-fluoro-phenyl)-ethylsulfanyl]-2-(2,2,2-trichloro-ethoxycarbonyl)-ethyl]-benzoic acid 2-phenyl-5-trifluoromethyl-oxazol-4-ylmethyl ester 
• 1055303-88-2 2-[2-(4-fluoro-phenyl)-ethylsulfanyl]-3-{4-[2-(4-methanesulfonyloxy-phenyl)-ethylsulfanylcarbonyl]-phenyl}-propionic acid 2,2,2-trichloro-ethyl ester 
• 1055303-24-6 4-{2-carboxy-2-[2-(4-fluoro-phenyl)-ethylsulfanyl]-ethyl}-benzoic acid 2-phenyl-5-trifluoromethyl-oxazol-4-ylmethyl ester 
• 1055304-23-8 C₂₈H₂₆Cl₃FO₇S₂ 
• 1055303-74-6 3-[4-(tert-butyl-dimethyl-silanyloxymethyl)-phenyl]-2-[2-(4-fluoro-phenyl)-ethylsulfanyl]-propionic acid 2,2,2-trichloro-ethyl ester 
• 1055303-13-3 4-methanesulfonyloxy-benzoic acid 4-{2-carboxy-2-[2-(4-fluoro-phenyl)-ethylsulfanyl]-ethyl}-benzyl ester 
• 1055303-19-9 2-[2-(4-fluoro-phenyl)-ethylsulfanyl]-3-[4-(2-phenyl-propionyloxymethyl)-phenyl]-propionic acid 
• 1055303-80-4 4-[2-[2-(4-fluoro-phenyl)-ethylsulfanyl]-2-(2,2,2-trichloro-ethoxycarbonyl)-ethyl]-benzoic acid 
• 1055303-73-5 3-[4-(tert-butyl-dimethyl-silanyloxymethyl)-phenyl]-2-[2-(4-fluoro-phenyl)-ethylsulfanyl]-propionic acid 
• 1055303-75-7 2-[2-(4-fluoro-phenyl)-ethylsulfanyl]-3-(4-hydroxymethyl-phenyl)-propionic acid 2,2,2-trichloro-ethyl ester 
• 405219-34-3 2-(4-fluoro-phenyl)-ethanesulfonyl chloride 

Relevant articles and documents

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Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS.

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The present invention relates to 2-(substituted sulphur, sulphone or sulphoxide)-3-(substituted phenyl) propionic acid derivatives, 2-(substituted oxygen)-3-(substituted phenyl) propionic acid derivatives, benzoic acid derivatives, and derivatives of 2-methyl-2-(phenoxy or phenylthio)propanoic acid and 2-(methylor ethyl)-2-(phenoxy or phenylthio)butanoic acid, to processes for preparing such compounds, to their use in the treatment of inflammatory conditions, and to pharmaceutical compositions containing them.