105552-03-2

Basic information

• Product Name: (1R,1'R)-1-ethyl-N-2'-hydroxy-1'-phenylethyl-N-methyl-2-phenylethylamine
• CAS NO: 105552-03-2
• Molecular Weight: 283.414
• Mol File: 105552-03-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (1R,1'R)-1-ethyl-N-2'-hydroxy-1'-phenylethyl-N-methyl-2-phenylethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,1'R)-1-ethyl-N-2'-hydroxy-1'-phenylethyl-N-methyl-2-phenylethylamine(105552-03-2)
• EPA Substance Registry System: (1R,1'R)-1-ethyl-N-2'-hydroxy-1'-phenylethyl-N-methyl-2-phenylethylamine(105552-03-2)

Safety Data

• Hazardous Substances Data: 105552-03-2(Hazardous Substances Data)

Upstream product

• 105551-96-0 (2S,4R)-2-ethyl-N-methyl-4-phenyl-1,3-oxazolodine 
• 73085-90-2 benzyltitanium triisopropoxide 
• 6921-34-2 benzylmagnesium chloride 
• 122-78-1 phenylacetaldehyde 
• 925-90-6 ethylmagnesium bromide 
• 105562-20-7 (2S,4R)-2-benzyl-N-methyl-4-phenyl-1,3-oxazolodine 
• 84773-28-4 (R)-2-(methylamino)-2-phenylethanol 
• 1589-82-8 phenylmagnesium bromide 

Relevant articles and documents

ASYMMETRIC INDUCTION BY CHIRAL HETEROCYCLIC COMPOUNDS: REACTION OF CHIRAL N-METHYL-4-PHENYL-1,3-OXAZOLIDINES WITH ORGANOMETALLIC REAGENTS

The reaction of (2S,4R)-2-alkyl-N-methyl-4-phenyl-1,3-oxazolidines (1a-c) with Grignard reagent gave (1R,1'R)-form compounds (2a-c) as the major product.On the contrary, the reaction of 1a-c with organotitanium reagent gave (1S,1'R)-form compounds (3a-c) as the major product.This stereoselectivity is a remarkable characteristic of the reaction of 1,3-oxazolidines with organometallic reagents.