10557-85-4

Basic information

• Product Name: 4-Iodo-3,5-dimethylisoxazole
• Synonyms: 3,5-DIMETHYL-4-IODOISOXAZOLE;4-IODO-3,5-DIMETHYLISOXAZOLE;BUTTPARK 97\06-60;3,5-DIMETHYL-4-IODOISOXAZOLE 97%;3.5-dimethyl-4-iodoisorazole;3,5-diMethyl-4-iodoMethylisoxazole
• CAS NO: 10557-85-4
• Molecular Formula: C₅H₆INO
• Molecular Weight: 223.01
• Product Categories: Halogenated;Isoxazole;Organohalides
• Mol File: 10557-85-4.mol
• Article Data: 6

Chemical Properties

• Melting Point: 51 °C
• Boiling Point: 239.2 °C at 760 mmHg
• Flash Point: 98.5 °C
• Appearance: /
• Density: 1.8763 (estimate)
• Vapor Pressure: 0.0628mmHg at 25°C
• Refractive Index: 1.566
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• PKA: -2.30±0.28(Predicted)
• Sensitive: Light Sensitive
• CAS DataBase Reference: 4-Iodo-3,5-dimethylisoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Iodo-3,5-dimethylisoxazole(10557-85-4)
• EPA Substance Registry System: 4-Iodo-3,5-dimethylisoxazole(10557-85-4)

Safety Data

• Statements: 41
• Safety Statements: 24/25-39-26
• HazardClass: LIGHT SENSITIVE
• Hazardous Substances Data: 10557-85-4(Hazardous Substances Data)

Usage

General Description

4-Iodo-3,5-dimethylisoxazole is a chemical compound with the molecular formula C6H6INO. It is a substituted isoxazole, which is a five-membered heterocyclic ring containing an oxygen and a nitrogen atom. The presence of the iodo and methyl groups on the isoxazole ring gives this compound unique chemical properties and makes it useful in various synthetic reactions and pharmaceutical applications. It is commonly used as a building block in the synthesis of complex organic molecules and pharmaceuticals due to its reactivity and ability to undergo various chemical transformations. Additionally, 4-Iodo-3,5-dimethylisoxazole may also have potential biological activities that make it of interest in the field of medicinal chemistry and drug discovery. Overall, this compound is valuable in the field of organic chemistry and has potential for various applications in synthesis and pharmaceutical research.

InChI:InChI=1/C5H6INO/c1-3-5(6)4(2)8-7-3/h1-2H3

Upstream product

• 300-87-8 3,5-dimethyl-1,2-oxazole 
• 16114-47-9 3,5-dimethylisoxazole-4-boronic acid 

Downstream Products

• 55841-23-1 (3,5-dimethyl-isoxazol-4-yl)-(2-nitro-phenyl)-methanol 
• 16114-47-9 3,5-dimethylisoxazole-4-boronic acid 
• 81190-81-0 3,5-dimethyl-4-trans-styrylisoxazole 
• 80536-46-5 3-methyl-5-pentylisoxazole 
• 154822-65-8 3,5-dimethyl-4-(4-methylphenyl)isoxazole 
• 154822-66-9 3,5-dimethyl-4-[4-(methyloxy)phenyl]isoxazole 
• 4345-46-4 3,5-dimethyl-4-phenyl-isoxazole 
• 60467-16-5 (2-chloro-phenyl)-(3,5-dimethyl-isoxazol-4-yl)-methanol 
• 81022-96-0 3,5-dimethyl-4-phenylethynylisoxazole 
• 90672-47-2 (3,5-Dimethyl-isoxazol-4-yl)-o-tolyl-methanol 
• 90672-49-4 <4-(1-methylethyl)phenyl>(3,5-dimethylisoxazol-4-yl)carbinol 
• 300-87-8 3,5-dimethyl-1,2-oxazole 
• 38604-92-1 3,5,3',5'-tetramethyl-[4,4']biisoxazolyl 
• 75632-81-4 3,5-dimethyl-4-(trimethylsilyl)isoxazole 

Relevant articles and documents

A new, mild one-pot synthesis of iodinated heterocycles as suitable precursors for N-heterocyclic carbene complexes

The use of I2/AgOAc in dichloromethane constitutes a cheap, mild, and efficient method for the selective iodination of a variety of heterocycles. In a number of cases, this method provides superior yields to other literature methods and affords iodo-functionalized heterocycles that are suitable precursors for carbene complexes.

Structure-based design of orally bioavailable 1 h -Pyrrolo[3,2- C ]pyridine inhibitors of mitotic kinase monopolar spindle 1 (MPS1)

The protein kinase MPS1 is a crucial component of the spindle assembly checkpoint signal and is aberrantly overexpressed in many human cancers. MPS1 is one of the top 25 genes overexpressed in tumors with chromosomal instability and aneuploidy. PTEN-defic

IMIDAZO [4, 5-C] QUINOLINE DERIVATES AS BROMODOMAIN INHIBITORS

Novel compounds of Formula (I) and salts thereof, pharmaceutical compositions containing such compounds and their use in therapy.