105615-58-5Relevant articles and documents
New anthracycline antibiotics 10-epi-oxaunomycin and 10-epi-11-deoxyoxaunomycin
Johdo,Nishida,Okamoto,Yoshimoto,Takeuchi
, p. 1153 - 1158 (2007/10/03)
Two new anthracycline antibiotics, 10-epi-oxaunomycin and 10-epi-11-deoxyoxaunomycin, were photochemically obtained from anthracycline metabolites D788-1 (10-carboxy-13-deoxocarminomycin) and D788-3 (10-carboxy-11-deoxy-13-deoxocarminomycin) and were examined for their growth inhibitory activities on cultured L1210 leukemic cells. Effects of the S configuration of C-10 and a hydroxyl group at C-11 on the bioactivity are discussed in comparison with oxaunomycin and 11-deoxyoxaunomycin.
A novel method for regio- and stereoselective hydroxylation of anthracycline glycosides
Nakajima,Kawai,Sakakibara,Tatsuta,Otake
, p. 4857 - 4858 (2007/10/02)
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