1060815-67-9 Usage
Description
6-Bromo-2-chloronicotinic acid is an organic compound that features a nicotinic acid structure with a bromine atom at the 6th position and a chlorine atom at the 2nd position. It is a valuable intermediate in the synthesis of various pharmaceuticals and agrochemicals due to its unique structural features and reactivity.
Uses
Used in Pharmaceutical Industry:
6-Bromo-2-chloronicotinic acid is used as a key intermediate for the synthesis of aminopyridyl carboxylates, which are important building blocks in the development of various pharmaceuticals. The regioselective copper(I)-catalyzed Ullmann amination using sodium azide allows for the efficient preparation of these valuable compounds.
Used in Agrochemical Industry:
6-Bromo-2-chloronicotinic acid is also utilized in the synthesis of agrochemicals, specifically as a precursor for the development of novel pesticides and herbicides. Its unique structure and reactivity contribute to the creation of effective and targeted agrochemical products.
Check Digit Verification of cas no
The CAS Registry Mumber 1060815-67-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,6,0,8,1 and 5 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1060815-67:
(9*1)+(8*0)+(7*6)+(6*0)+(5*8)+(4*1)+(3*5)+(2*6)+(1*7)=129
129 % 10 = 9
So 1060815-67-9 is a valid CAS Registry Number.
1060815-67-9Relevant articles and documents
Synthesis method for 2-chloro-6-bromo-3-pyridylaldehyde
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Paragraph 0008; 0009; 0010, (2017/11/04)
The invention relates to a synthesis method for 2-chloro-6-bromo-3-pyridylaldehyde and mainly aims at solving the technical problem that an effective synthesis method has not been found at present. The synthesis method comprises the following steps of oxidizing ethyl 2-chloronicotinate to obtain a compound 1; reacting the compound 1 with phosphorus oxide bromide in acetonitrile to generate a compound 2; reacting the compound 2 with diisobutyl aluminum hydride, reducing ester group into hydroxyl to generate a compound 3; and reacting the compound 3 with Dess-Martin periodinane and oxidizing the hydroxyl into an aldehyde group to generate a target compound 4. The 2-chloro-6-bromo-3-pyridylaldehyde is widely applied to the pharmaceutical industry as a medical intermediate.