1063628-80-7

Basic information

• Product Name: 2-(2-((4-amino-2-(methylthio)pyrimidin-5-yl)methylene)hydrazono)-3-cyclohexylthiazolidin-4-one
• CAS NO: 1063628-80-7
• Molecular Weight: 364.495
• Mol File: 1063628-80-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(2-((4-amino-2-(methylthio)pyrimidin-5-yl)methylene)hydrazono)-3-cyclohexylthiazolidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-((4-amino-2-(methylthio)pyrimidin-5-yl)methylene)hydrazono)-3-cyclohexylthiazolidin-4-one(1063628-80-7)
• EPA Substance Registry System: 2-(2-((4-amino-2-(methylthio)pyrimidin-5-yl)methylene)hydrazono)-3-cyclohexylthiazolidin-4-one(1063628-80-7)

Safety Data

• Hazardous Substances Data: 1063628-80-7(Hazardous Substances Data)

Upstream product

• 1063629-02-6 1-((4-amino-2-(methylthio)pyrimidin-5-yl)methylene)-4-cyclohexylthiosemicarbazide 
• 105-36-2 ethyl bromoacetate 

Relevant articles and documents

Synthesis and characterization of new thiazolidin-4-one derivatives

The synthesis of some new functionalized thiazolidin-4-one derivatives has been described. The N-substituted-thiosemicarbazides 3a-3i were obtained though the reaction of alkylamines 2a-2i, carbon disulfide, and hydrazine hydrate. The condensation reaction between 3a-3i and 4-amino-2-methanesulfanylpyrimidine-5- carboxaldehyde 1 afforded the thiosemicarbazones 4a-4i. The corresponding thiazolidin-4-ones 5a-5i were prepared by cyclization of 4a-4i with ethyl bromoacetate. The structures of the final products were confirmed by IR, 1H NMR, 13C NMR, and HRMS.