1065604-64-9

Basic information

• Product Name: ethyl 4-(4-((2-(4-chlorophenyl)cyclohex-1-enyl)methyl)piperazin-1-yl)benzoate
• Synonyms: ethyl 4-(4-((2-(4-chlorophenyl)cyclohex-1-enyl)methyl)piperazin-1-yl)benzoate
• CAS NO: 1065604-64-9
• Molecular Weight: 438.997
• Mol File: 1065604-64-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: ethyl 4-(4-((2-(4-chlorophenyl)cyclohex-1-enyl)methyl)piperazin-1-yl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-(4-((2-(4-chlorophenyl)cyclohex-1-enyl)methyl)piperazin-1-yl)benzoate(1065604-64-9)
• EPA Substance Registry System: ethyl 4-(4-((2-(4-chlorophenyl)cyclohex-1-enyl)methyl)piperazin-1-yl)benzoate(1065604-64-9)

Safety Data

• Hazardous Substances Data: 1065604-64-9(Hazardous Substances Data)

Upstream product

• 1065604-49-0 ethyl 4-(4-((2-bromocyclohex-1-enyl)methyl)piperazin-1-yl)benzoate 
• 1679-18-1 4-Chlorophenylboronic acid 
• 1228784-09-5 2-(4-chlorophenyl)cyclohex-1-ene-1-carbaldehyde 
• 80518-57-6 ethyl 4-(piperazin-1-yl)benzoate 

Downstream Products

• 916204-04-1 4-(4-((2-(4-chlorophenyl)cyclohex-1-enyl)methyl)piperazin-1-yl)benzoic acid 

Relevant articles and documents

APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES

Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.

Discovery of an orally bioavailable small molecule inhibitor of prosurvival B-cell lymphoma 2 proteins

Overexpression of prosurvival proteins such as Bcl-2 and Bcl-XL has been correlated with tumorigenesis and resistance to chemotherapy, and thus, the development of antagonists of these proteins may provide a novel means for the treatment of can