106782-78-9

Basic information

• Product Name: 3-METHOXY-2-AMINOBENZAMIDE
• Synonyms: 3-METHOXY-2-AMINOBENZAMIDE;2-AMino-M-anisaMide
• CAS NO: 106782-78-9
• Molecular Formula: C₈H₁₀N₂O₂
• Molecular Weight: 166.1772
• Product Categories: Aromatics Compounds;Aromatics
• Mol File: 106782-78-9.mol
• Article Data: 19

Chemical Properties

• Melting Point: 162-164°C
• Boiling Point: 280.7±25.0 °C(Predicted)
• Appearance: /
• Density: 1.236±0.06 g/cm3(Predicted)
• Storage Temp.: -20°C Freezer
• Solubility: DMSO, Methanol
• PKA: 15.58±0.50(Predicted)
• CAS DataBase Reference: 3-METHOXY-2-AMINOBENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHOXY-2-AMINOBENZAMIDE(106782-78-9)
• EPA Substance Registry System: 3-METHOXY-2-AMINOBENZAMIDE(106782-78-9)

Safety Data

• Hazardous Substances Data: 106782-78-9(Hazardous Substances Data)

Usage

Description

3-Methoxy-2-aminobenzamide, with the chemical formula C8H10N2O2 and CAS number 106782-78-9, is an organic compound characterized by a white solid appearance. It is primarily recognized for its utility in organic synthesis, where it serves as a valuable intermediate for the creation of various complex organic molecules.

Uses

Used in Organic Synthesis:
3-Methoxy-2-aminobenzamide is used as a synthetic intermediate for the development of a range of organic compounds. Its unique structure, featuring a methoxy group and an amide functionality, allows it to be a versatile building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-Methoxy-2-aminobenzamide is utilized as a key component in the synthesis of potential drug candidates. Its presence in the molecular structure can influence the pharmacological properties, such as solubility, stability, and bioavailability, which are critical for drug efficacy and safety.
Used in Research and Development:
3-Methoxy-2-aminobenzamide also plays a significant role in research and development settings, where it is employed to explore new chemical reactions and synthetic pathways. Its reactivity and functional groups make it an attractive candidate for studying novel synthetic methodologies and for the preparation of new compounds with potential applications in various fields.
Used in Agrochemicals:
In the agrochemical sector, 3-Methoxy-2-aminobenzamide is used as a precursor in the synthesis of active ingredients for pesticides and herbicides. Its incorporation into these molecules can contribute to the development of more effective and environmentally friendly agrochemical products.
Overall, 3-Methoxy-2-aminobenzamide is a multifaceted compound with applications spanning across various industries, primarily due to its role in organic synthesis and its potential to contribute to the development of new and improved products in pharmaceuticals, agrochemicals, and beyond.

Upstream product

• 15865-57-3 2-nitro-3-methoxybenzoyl chloride 
• 4920-80-3 3-methoxy-2-nitrobenzoic acid 
• 34954-65-9 3-methoxyisatoic anhydride 
• 372077-48-0 C₈H₈ClNO₂ 
• 3177-80-8 2-amino-3-methoxybenzoic acid 
• 99595-85-4 3-methoxy-2-nitro-benzamide 

Downstream Products

• 150479-56-4 2-(2-ethoxybenzamido)-3-methoxybenzamide 
• 869298-98-6 ethyl ((2-(aminocarbonyl)-6-methoxyphenyl)amino)(oxo)acetate 
• 1227361-52-5 C₇H₇BrN₂O₂ 
• 220115-26-4 2-(4-aminophenyl)-8-methoxyquinazolin-4-one 
• 172462-89-4 NU 1065 
• 220115-16-2 3-methoxy-2-(4-nitrobenzamido)benzamide 
• 172462-99-6 2-benzamido-3-methoxybenzamide 
• 864179-28-2 7,8-dehydro-1-methoxyrutaecarpine 
• 1246250-64-5 2-[4-(2-hydroxy-ethoxy)-3,5-dimethyl-phenyl]-8-methoxy-3H-quinazolin-4-one 
• 869294-78-0 ethyl 8-(methyloxy)-4-oxo-3,4-dihydroquinazoline-2-carboxylate 
• 1361455-62-0 2-(4-fluorophenyl)-8-hydroxyquinazolin-4-one 
• 1361456-62-3 2-(4-bromophenyl)-8-hydroxyquinazolin-4-one 
• 220115-32-2 8-hydroxy-2-(4-methylphenyl)quinazolin-4-one 

Relevant articles and documents

Synthesis and nematicidal evaluation of 1,2,3-benzotriazin-4-one derivatives containing piperazine as linker against Meloidogyne incognita

To explore new skeleton with nematicidal activity, a series of novel 1,2,3-benzotriazin-4-one derivatives containing piperazine as linker were synthesized and varied fragments were also introduced to increase structure diversity of the new skeleton. Their inhibitory activities in vivo were evaluated against Meloidogyne incognita. The newly prepared compounds A6, A8, A21, A28 and A38 exhibited more than 50% inhibition at the concentration of 20 mg/L. Especially compound A6 displayed 71.4% inhibition against Meloidogyne incognita at the concentration of 20 mg/L. The nematicidal activities varied significantly depending on the types and positions of the substituents, which provided guidance for further structure modification.

Synthesis and nematicidal activities of 1,2,3-benzotriazin-4-one containing 4,5-dihydrothiazole-2-thiol derivatives against Meloidogyne incognita

A series of novel 1,2,3-benzotriazin-4-one derivatives containing 4,5-dihydrothiazole-2-thiol were synthesized and characterized by 1H NMR, 13C NMR, 19F NMR and HRMS. The bioassay results showed that compounds 3-(3-((4,5-dihydrothiazol-2-yl)thio)propyl)-7-methoxybenzo[d][1–3]triazin-4(3H)-one, 3-(3-((4,5-dihydrothiazol-2-yl)thio)propyl)-6-nitrobenzo[d][1–3]triazin-4(3H)-one, 7-chloro-3-(3-((4,5-dihydrothiazol-2-yl)thio)propyl)benzo[d][1–3]triazin-4(3H)-one exhibited good control efficacy against the cucumber root-knot nematode disease caused by Meloidogyne incognita at the concentration of 10.0 mg L?1 in vivo. Compound 7-chloro-3-(3-((4,5-dihydrothiazol-2-yl)thio)propyl)benzo[d][1–3]triazin-4(3H)-one showed excellent nematicidal activity with inhibition 68.3% at a concentration of 1.0 mg L?1. It suggested that the structure of 1,2,3-benzotriazin-4-one containing 4,5-dihydro-thiazole-2-thiol could be optimized further.

Substituted fused pyrimidinone and dihydro-pyrimidone

The use of substituted fused pyrimidinones and dihydropyrimidinones of the formula (I) or salts thereof where the radicals of the formula (I) are each as defined in the description, for enhancing stress tolerance in plants to abiotic stress, and for invigorating plant growth and/or for increasing plant yield.