106797-53-9

Basic information

• Product Name: 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone
• Synonyms: 2-hydroxy-1-(4-(2-hydroxyethoxy)phenyl)-2-methyl-1-propanon;2-hydroxy-1-(4-(2-hydroxyethoxy)phenyl)-2-methyl-1-propanone;2-hydroxy-1-[4-(2-hydroxyethoxy)phenyl]-2-methyl-1-propanon;darocur2959;2-HYDROXY-4'-(2-HYDROXYETHOXY)-2-METHYLPROPIOPHENONE;1-[4-(2-HYDROXYETHOXY)-PHENYL]-2-HYDROXY-2-METHYL-1-PROPANE-1-ONE;LABOTEST-BB LT00452333;2-Hydroxy-[4'-(2-Hydroxyethoxy)Phenyl]-2-Methyl Propanone
• CAS NO: 106797-53-9
• Molecular Formula: C₁₂H₁₆O₄
• Molecular Weight: 224.25
• EINECS: 402-670-3
• Product Categories: Acetophenone;Organic Photoinitiators;Polymerization Initiators
• Mol File: 106797-53-9.mol
• Article Data: 8

Chemical Properties

• Melting Point: 88-90 °C(lit.)
• Boiling Point: 405 °C at 760 mmHg
• Flash Point: 155.8 °C
• Appearance: /
• Density: 1.183 g/cm³
• Vapor Pressure: 0Pa at 25℃
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• PKA: 12.96±0.29(Predicted)
• Water Solubility: 7.6g/L at 25℃
• CAS DataBase Reference: 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone(106797-53-9)
• EPA Substance Registry System: 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone(106797-53-9)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 2
• RTECS: UC2976000
• Hazardous Substances Data: 106797-53-9(Hazardous Substances Data)

Usage

Description

2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone(Photoinitiator 2959) has been tested for use in UV curing formulations on wood, metal, plastic and paper surfaces.It has lower volatility and odor compared to Irgacure 1173. Importantly, the reactive hydroxyl groups of it are easily grafted onto the polymer molecules, making it more convenient to process.

Uses

2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone is a photoinitiator allowed by the FDA certification system; it can be used in water-based photocuring systems, with high melting point, and can also be used in UV-curable powder coatings; it is a high-efficiency non-yellowing UV photoinitiator. UV polymerization of saturated prepolymerized systems.

Upstream product

• 108-94-1 cyclohexanone 
• 6192-44-5 2-phenoxyethyl acetate 
• 159119-01-4 1-(4-(2-hydroxyethoxy)phenyl)-2-methylpropan-1-one 
• 106797-52-8 4-(2-acetoxyethoxy)-phenyl 2-propyl ketone 

Downstream Products

• 115055-21-5 2-[p-(2-hydroxy-2-methylpropiophenone)]-ethylene glycol-methacrylate 
• 119462-64-5 1-[4-(2-azidoethoxy)phenyl]-2-hydroxy-2-methylpropan-1-one 
• 110186-64-6 1-[4-(2-aminoethoxy)phenyl]-2-hydroxy-2-methylpropan-1-one 

Relevant articles and documents

Preparation method of alpha-hydroxyketone photoinitiator

The invention provides a preparation method of an alpha-hydroxyketone photoinitiator. The preparation method comprises the steps of taking a ketone compound and a trihalomethyl-substituted benzene anda derivative thereof as raw materials, enabling the raw materials to react under the action of a polar solvent and a metal catalyst to form a halogenated intermediate in one step, and hydrolyzing theobtained product under the action of an alkali metal hydroxide aqueous solution and a phase transfer catalyst to obtain the alpha-hydroxyketone photoinitiator. The operation is simple, the reaction step is short, no Lewis acid catalyst is used in the reaction, the pollution is small, the catalyst can be recycled, by-products are less, the cost is low, and a variety of products can be produced bythe same method.

Preparation method for 2-hydroxy-1-[4-(2-hydroxyethoxy)phenyl]-2-methyl-1-acetone

The invention provides a preparation method for a hydroxy-ketone photoinitiator, i.e., 2-hydroxy-1-[4-(2-hydroxyethoxy)phenyl]-2-methyl-1-acetone. In tradition production processes, chlorine or liquid bromine is used as a halogenation reagent, and halogenation and hydrolysis are successively carried out so as to obtain a target product; however, chlorine is severely poisonous gas prone to leakage while liquid bromine is easily volatile liquid with strong toxicity and corrosivity and produces a great amount of acidic exhaust gas in the process of halogenation, which leads to production of a great amount of waste water in the process of aftertreatment. The preparation method provided by the invention avoids usage of chlorine or liquid bromine as the halogenation reagent and directly prepares the target product in one step by using a carbon tetrachloride process. The preparation method provided by the invention has the advantages that the amount of exhaust gas produced in the process of reaction is small; feeding and aftertreatment are simple to operate; the output of wastewater is low; product content reaches 99% or above; and production cost is low.

I2- or NBS-catalyzed highly efficient α-hydroxylation of ketones with dimethyl sulfoxide

An efficient method for the direct preparation of high synthetic valuable α-hydroxycarbonyls is described. The simple and readily available I2 or NBS was used as catalyst. DMSO acts as the oxidant, oxygen source, and solvent. A diverse range of tertiary Csp3-H bonds as well as more challenging secondary Csp3-H bonds could be hydroxylated in this transformation. The reaction is mild, less toxic and easy to perform.