106914-07-2

Basic information

• Product Name: N-Methyl-2-amino-2-methylpropionamide
• Synonyms: N-Methyl-2-amino-2-methylpropionamide;N~1~,2-dimethylalaninamide(SALTDATA: HCl);2-AMino-N,2-diMethyl-propanaMide;N~1~,2-dimethylalaninamide
• CAS NO: 106914-07-2
• Molecular Formula: C₅H₁₂N₂O
• Molecular Weight: 116
• Mol File: 106914-07-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 250.5 °C at 760 mmHg
• Flash Point: 105.3 °C
• Appearance: /
• Density: 0.962 g/cm³
• PKA: 17.55±0.46(Predicted)
• CAS DataBase Reference: N-Methyl-2-amino-2-methylpropionamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-Methyl-2-amino-2-methylpropionamide(106914-07-2)
• EPA Substance Registry System: N-Methyl-2-amino-2-methylpropionamide(106914-07-2)

Safety Data

• Hazardous Substances Data: 106914-07-2(Hazardous Substances Data)

Usage

General Description

N-Methyl-2-amino-2-methylpropionamide is a chemical compound with the molecular formula C5H10N2O. Also known as N-methylalaninamide, it is an organic amide that consists of a methyl substituent attached to the nitrogen atom of alaninamide. N-Methyl-2-amino-2-methylpropionamide is mainly used as a building block in pharmaceutical and chemical synthesis, particularly in the preparation of various pharmaceutical drugs. It is also utilized in the development of certain organic reactions and catalytic processes due to its unique structural properties. Additionally, N-Methyl-2-amino-2-methylpropionamide has applications in the field of medicinal chemistry as a potential candidate for drug discovery and development.

Upstream product

• 1113-49-1 2-methylalanine ethyl ester 
• 74-89-5 methylamine 
• 84827-08-7 tert-butyl (2-methyl-1-(methylamino)-1-oxopropan-2-yl)carbamate 
• 15028-41-8 methyl 2-aminoisobutyrate hydrochloride 

Downstream Products

• 1050227-23-0 Boc-Gpn-Aib-NHMe 
• 126059-31-2 (-)-N-methyl-2-(2-hydroxy-3-(2-methoxy-phenoxy)-propylamino)-2-methyl-propionamide 

Relevant articles and documents

DIPEPTIDE ANALOGS AS TGF-BETA INHIBITORS

The present disclosure is concerned with dipeptide analogs that are capable of inhibiting TGF-β and methods of treating cancers such as, for example, multiple myeloma and a hematologic malignancy, methods for immunotherapy, and methods of treating fibroti

The photochemistry of N-p-toluenesulfonyl peptides: The peptide bond as an electron donor

The scope of photobiological processes that involve absorbers within a protein matrix may be limited by the vulnerability of the peptide group to attack by highly reactive redox centers consequent upon electronic excitation. We have explored the nature of this vulnerability by undertaking comprehensive product analyses of aqueous photolysates of 12 N-p-toluene-sulfonyl peptides with systematically selected structures. The results indicate that degradation includes a major pathway that is initiated by intramolecular electron transfer in which the peptide bond serves as electron donor, and the data support the likelihood' of a relay process in dipeptide derivatives.