107-96-0Relevant articles and documents
Reduction Potentials and Exchange Reactions of Thiyl Radicals and Disulfide Anion Radicals
Surdhar, Parminder S.,Armstrong, David A.
, p. 6532 - 6537 (1987)
Redox equilibria between RS. and -S-S-- radicals, and between these types of radical and phenoxyl and chlorpromazine (ClPz.2+) radicals, have been investigated in aqueous solutions at pHs over the range 6-10 to obtain a self-consistent set of redox potentials for the reactions PhO. + H+ + e- = PhOH (4), RSS.R + 2H+ + e- = 2RSH (11), and RS. + H+ + e- = RSH (18), in sulfur systems with alkyl R groups.Absolute standard potentials were calculated on the of E0 = 0.83 V for the chlorpromazine couple.The results for E04 (=1.35 +/- 0.02 V) and E018 (=1.33 +/- 0.02 V) were in agreement with values calculated from thermodynamic data within the known uncertainties.E018 was found to exhibit a falloff when electron-rich groups, such as the two methyls of penicillamine or the CO2- of β-mercaptoacetic acid, were present on the carbon adjacent to the S atom.However, the effect was relatively small (ca. 10-14 mV).E011 was 1.72 +/- 0.02 V for β-mercaptoethanol.The corresponding potentials for the cyclic anions of dithiothreitol, dithioerythritol, and lipoamide were the same within experimental error, but the uncertainties were larger (+/- 0.04 V).For the reaction e- + -S-S- = -S-S-- (22), the magnitude of E022 was calculated to be -1.60 V, showing that only strongly reducing species could donate electrons to disulfide.Rate constants for several of the forward and backward reactions in the equilibria were also determined.
Method for preparing mercaptocarboxylic acid or derivatives thereof by aminolysis of thioureidocarboxylic acid or derivatives thereof
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Paragraph 0008, (2020/06/09)
The invention relates to a method for preparing mercaptocarboxylic acid or derivatives thereof by aminolysis of thioureidocarboxylic acid or derivatives thereof. The method mainly comprises the following steps: 1, dissolving thioureidocarboxylic acid or a derivative thereof in ammonia water or a mixed solution of ammonia water and a cosolvent, heating the system to 40-150 DEG C, and reacting for long time until reaction of the thioureido salt is finished; 2, cooling the reaction system, neutralizing the reaction system by using acid, removing the solvent by using a solvent extraction system, and separating to obtain the mercaptocarboxylic acid or the derivative thereof; and 3, concentrating and filtering the residual water phase or organic phase, recycling the distilled water phase or organic phase, and taking the solid ammonium salt mixture as a nitrogen fertilizer. According to the method, the defects that pollutants are complex and difficult to treat, and the environment is pollutedin the prior art that metal ions such as NaOH are adopted for alkaline hydrolysis of thioureidocarboxylic acid and derivatives thereof to prepare mercaptocarboxylic acid and derivatives thereof are overcome. The method has the advantages of simple process, low cost, no environmental pollution and the like, and can basically realize zero emission of three wastes.
Thiourea derivative and thiohydracrylic acid parallel production method
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Paragraph 0053; 0054, (2019/03/25)
The invention belongs to the technical field of organic synthesis and particularly discloses a thiourea derivative and thiohydracrylic acid parallel production method. The thiourea derivative and thiohydracrylic acid parallel production method comprises neutralizing and aminolyzing S-acrylic-dithiocarbamate in aqueous or organic solvent to obtain thiourea derivatives and the by-product of 3-mercapto propionate, wherein the 3-mercapto propionate is acidized into 3-mercapto propionic acid. The thiourea derivative and thiohydracrylic acid parallel production method provides a practical method forsynthesis of the thiourea derivatives and the 3-mercapto propionic acid and has the advantages of being mild in reaction, short in reaction time, simple in technical process and high in yield of thethiourea derivatives and the 3-mercapto propionic acid, thereby achieving certain industrial economic values.
