107027-43-0 Usage
Quinoline derivative
A quinoline-based compound This refers to the fact that the compound is derived from the quinoline structure, which is a core structure in many pharmaceutical drugs.
Substituted phenyl ring
4-chlorophenyl group The phenyl ring in the compound is substituted with a chlorine atom at the 4-position, which can influence the compound's biological activity and properties.
Carboxylic acid functional group
4-carboxylic acid The presence of a carboxylic acid group in the compound provides it with acidic properties and can participate in various chemical reactions and interactions with biological targets.
Pharmaceutical applications
Potential activity against diseases Due to its structural similarity to other quinoline-based drugs, 2-(4-chlorophenyl)-8-methylquinoline-4-carboxylic acid may have potential applications in treating various diseases, such as malaria, cancer, and microbial infections.
Chlorophenyl and methyl groups
Possible interesting biological activities The presence of these groups in the compound's structure may offer unique biological activities, making it a promising candidate for further research and development in medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 107027-43-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,7,0,2 and 7 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 107027-43:
(8*1)+(7*0)+(6*7)+(5*0)+(4*2)+(3*7)+(2*4)+(1*3)=90
90 % 10 = 0
So 107027-43-0 is a valid CAS Registry Number.
InChI:InChI=1/C17H12ClNO2/c1-10-3-2-4-13-14(17(20)21)9-15(19-16(10)13)11-5-7-12(18)8-6-11/h2-9H,1H3,(H,20,21)
107027-43-0Relevant articles and documents
Potential antitumor agents. 57. 2-Phenylquinoline-8-carboxamides as 'minimal' DNA-intercalating antitumor agents with in vivo solid tumor activity
Atwell,Baguley,Denny
, p. 396 - 401 (2007/10/02)
A series of phenyl-substituted derivatives of the 'minimal' DNA-intercalating agent N-[2-(dimethylamino)-ethyl]-2-phenylquinoline-8-carboxamide (1) have been synthesized and evaluated for in vivo antitumor activity, in a continuing search for active compo
