1071575-26-2

Basic information

• Product Name: 1-[2-(1-methyl-piperidin-3-yl-methoxy)-5-trimethylsilanylethynyl-phenyl]-3-(5-methyl-pyrazin-2-yl)-urea
• Synonyms: 1-[2-(1-methyl-piperidin-3-yl-methoxy)-5-trimethylsilanylethynyl-phenyl]-3-(5-methyl-pyrazin-2-yl)-urea
• CAS NO: 1071575-26-2
• Molecular Weight: 451.644
• Mol File: 1071575-26-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[2-(1-methyl-piperidin-3-yl-methoxy)-5-trimethylsilanylethynyl-phenyl]-3-(5-methyl-pyrazin-2-yl)-urea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[2-(1-methyl-piperidin-3-yl-methoxy)-5-trimethylsilanylethynyl-phenyl]-3-(5-methyl-pyrazin-2-yl)-urea(1071575-26-2)
• EPA Substance Registry System: 1-[2-(1-methyl-piperidin-3-yl-methoxy)-5-trimethylsilanylethynyl-phenyl]-3-(5-methyl-pyrazin-2-yl)-urea(1071575-26-2)

Safety Data

• Hazardous Substances Data: 1071575-26-2(Hazardous Substances Data)

Upstream product

• 457098-83-8 5-methyl-pyrazine-2-carbonyl azide 
• 874747-19-0 2-(1-methyl-piperidin-3-ylmethoxy)-5-trimethylsilanylethynyl-phenylamine 

Relevant articles and documents

BISARYLUREA DERIVATIVES USEFUL FOR INHIBITING CHK1

Aryl- and heteroaryl-substituted urea compounds useful in the treatment of diseases and conditions related to DNA damage or lesions in DNA replication are disclosed. Methods of making the compounds, and their use as therapeutic agents, for example, in treating cancer and other diseases characterized by defects in DNA replication, chromosome segregation, or cell division also are disclosed. Formula (I).