1071717-04-8

Basic information

• Product Name: 2,2,2-trichloro-1-(2,4-dimethoxy-phenyl)-ethanol
• CAS NO: 1071717-04-8
• Molecular Weight: 285.555
• Mol File: 1071717-04-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,2,2-trichloro-1-(2,4-dimethoxy-phenyl)-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,2-trichloro-1-(2,4-dimethoxy-phenyl)-ethanol(1071717-04-8)
• EPA Substance Registry System: 2,2,2-trichloro-1-(2,4-dimethoxy-phenyl)-ethanol(1071717-04-8)

Safety Data

• Hazardous Substances Data: 1071717-04-8(Hazardous Substances Data)

Upstream product

• 75-87-6 chloral 
• 151-10-0 1,3-Dimethoxybenzene 
• 56-23-5 tetrachloromethane 
• 613-45-6 2,4-Dimethoxybenzaldehyde 

Downstream Products

• 934372-01-7 1,1-dichloro-2-(2,4-dimethoxyphenyl)ethene 
• 107447-29-0 acetic acid 2,2,2-trichloro-1-(2,4-dimethoxy-phenyl)-ethyl ester 

Relevant articles and documents

Suzuki-Miyaura cross-coupling of 1,1-dichloro-1-alkenes with 9-alkyl-9-BBN

We addressed an unexplored application of the Suzuki-Miyaura protocol to the cross-coupling of 1,1-dichloro-1-alkenes with 9-alkyl-9-BBN. The use of bisphosphine ligands with a large P-Pd-P bite angle allowed us to synthesize Z-chlorinated internal alkenes in good yields resulting from a selective monocoupling process, a recurrent challenge with 1,1-dichloro-1-alkenes. Moreover, these monochlorinated olefins could be further transformed providing stereospecifically trisubstituted olefins.