1072-68-0

Basic information

• Product Name: 1,4-DIMETHYLPYRAZOLE
• Synonyms: 1,4-DIMETHYL-1H-PYRAZOLE;1,4-DIMETHYLPYRAZOLE;Pyrazole, 1,4-dimethyl-;1,4-Dimethyl-1H-pyrazol
• CAS NO: 1072-68-0
• Molecular Formula: C₅H₈N₂
• Molecular Weight: 96.13
• EINECS: 1312995-182-4
• Mol File: 1072-68-0.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 145.592 °C at 760 mmHg
• Flash Point: 41.853 °C
• Appearance: /
• Density: 0.983 g/cm³
• Vapor Pressure: 6.09mmHg at 25°C
• Refractive Index: 1.518
• Storage Temp.: Room temperature.
• PKA: 2.80±0.10(Predicted)
• CAS DataBase Reference: 1,4-DIMETHYLPYRAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-DIMETHYLPYRAZOLE(1072-68-0)
• EPA Substance Registry System: 1,4-DIMETHYLPYRAZOLE(1072-68-0)

Safety Data

• Hazardous Substances Data: 1072-68-0(Hazardous Substances Data)

Usage

Description

1,4-Dimethylpyrazole, a chemical compound with the molecular formula C6H8N2, is a colorless solid that exhibits solubility in polar solvents. It is recognized for its diverse industrial applications and potential pharmaceutical uses, while also being noted for its low toxicity and minimal environmental and health risks when used with proper safety measures.

Uses

Used in Chemical Industry:
1,4-Dimethylpyrazole is used as a corrosion inhibitor for its ability to protect materials from degradation in corrosive environments, thereby extending their service life and reducing maintenance costs.
Used in Polymer Industry:
1,4-Dimethylpyrazole serves as a stabilizer for polymers, enhancing their resistance to degradation from environmental factors such as heat, light, and oxygen, which in turn improves the polymers' longevity and performance.
Used in Pharmaceutical Industry:
1,4-Dimethylpyrazole is used as a reagent in organic synthesis, contributing to the development of new pharmaceutical compounds and facilitating the synthesis of complex organic molecules.
Used in Research and Development:
1,4-Dimethylpyrazole is utilized in the investigation of its potential as a pharmaceutical agent, particularly as an inhibitor of cytochrome P450 enzymes, which are involved in the metabolism of various drugs and other substances in the body. This application could lead to advancements in drug interactions and efficacy studies.

InChI:InChI=1/C5H8N2/c1-5-3-6-7(2)4-5/h3-4H,1-2H3

Upstream product

• 7554-65-6 4-methyl-1H-pyrazole 
• 74-88-4 methyl iodide 
• 123-91-1 1,4-dioxane 
• 102-85-2 tri-n-butyl phosphite 
• 10602-37-6 1,1,3,3-tetraethoxy-2-methyl-propane 
• 7339-53-9 methyl hydrazine hydrochloride 
• 56-23-5 tetrachloromethane 
• 160886-90-8 2,4-dimethyl-2H-pyrazole-3-carbonyl chloride 

Downstream Products

• 4054-67-5 3,3',5,5'-tetramethyl-1H,1'H-4,4'-bipyrazole 
• 1383422-53-4 3-methyl-N-[(4-methyl-1H-pyrazol-1-yl)methyl]benzamide 
• 1047645-44-2 N-((1S)-2-amino-1-{[2-(trifluoromethyl)phenyl]methyl}ethyl)-4-(1,4-dimethyl-1H-pyrazol-5-yl)-2-thiophenecarboxamide hydrochloride 
• 1047645-51-1 5-chloro-4-(1,4-dimethyl-1H-pyrazol-5-yl)-N-((1S)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-1-{[2-(trifluoromethyl)phenyl]methyl}ethyl)-2-thiophenecarboxamide 
• 1047645-42-0 4-(1,4-dimethyl-1H-pyrazol-5-yl)-N-((1S)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-1-{[2-(trifluoromethyl)phenyl]methyl}ethyl)-2-thiophenecarboxamide 
• 1047644-57-4 N-((1S)-2-amino-1-{[2-(trifluoromethyl)phenyl]methyl}ethyl)-5-chloro-4-(1,4-dimethyl-1H-pyrazol-5-yl)-2-thiophenecarboxamide 
• 1047644-52-9 N-((1S)-2-amino-1-{[2-(trifluoromethyl)phenyl]methyl}ethyl)-4-(1,4-dimethyl-1H-pyrazol-5-yl)-2-thiophenecarboxamide 
• 1395443-04-5 3-iodo-1,4-dimethyl-1H-pyrazole 
• 1609470-39-4 C₁₂H₁₂F₂N₂O₂S 
• 1174834-52-6 1,4-dimethyl-1H-pyrazole-5-sulfonyl chloride 
• 1420531-80-1 (2-bromo-5-(trifluoromethyl)phenyl)(1,4-dimethyl-1H-pyrazol-5-yl)methanol 
• 1420531-85-6 ethyl 2-(3-(2-((1,4-dimethyl-1H-pyrazol-5-yl)methyl)-4-(trifluoromethyl)phenyl)-5-fluoro-1H-indol-1-yl)acetate 
• 1420531-84-5 3-(2-((1,4-dimethyl-1H-pyrazol-5-yl)methyl)-4-(trifluoromethyl)phenyl)-5-fluoro-1H-indole 
• 1420531-83-4 3-(2-((1,4-dimethyl-1H-pyrazol-5-yl)methyl)-4-(trifluoromethyl)phenyl)-5-fluoro-1-tosyl-1H-indole 

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