107246-26-4

Basic information

• Product Name: α-Benzyl-N-(1,2:3,4-di-O-cyclohexyliden-6-desoxy-α-D-galactopyranos-6-yliden)isoleucin-methylester
• CAS NO: 107246-26-4
• Molecular Weight: 555.712
• Mol File: 107246-26-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: α-Benzyl-N-(1,2:3,4-di-O-cyclohexyliden-6-desoxy-α-D-galactopyranos-6-yliden)isoleucin-methylester(CAS DataBase Reference)
• NIST Chemistry Reference: α-Benzyl-N-(1,2:3,4-di-O-cyclohexyliden-6-desoxy-α-D-galactopyranos-6-yliden)isoleucin-methylester(107246-26-4)
• EPA Substance Registry System: α-Benzyl-N-(1,2:3,4-di-O-cyclohexyliden-6-desoxy-α-D-galactopyranos-6-yliden)isoleucin-methylester(107246-26-4)

Safety Data

• Hazardous Substances Data: 107246-26-4(Hazardous Substances Data)

Upstream product

• 88820-79-5 1,2:3,4-Di-O-cyclohexyliden-α-D-galacto-hexodialdopyranose-(1,5) 
• 2577-46-0 L-isoleucine methyl ester 
• 100-39-0 benzyl bromide 
• 107246-16-2 N-(1,2:3,4-Di-O-cyclohexyliden-6-desoxy-α-D-galactopyranos-6-yliden)isoleucin-methylester 

Downstream Products

• 107246-38-8 (2S,3S)-2-Benzylisoleucin-methylester 
• 107246-38-8 (2R,3S)-2-Benzylisoleucin-methylester 

Relevant articles and documents

Asymmetric Synthesis of Methyl α-Alkyl-valinates, -leucinates, and -isoleucinates Using (Cyclohexylidene-protected) D-Galactodialdehyde as Chiral Auxiliary

The Schiff bases 2 from protected D-galactodialdehyde 1 and methyl valinate, -leucinate, and -isoleucinate were diastereoselectively alkylated via the lithium derivatives 3.The asymmetric induction of the alkylation step varied from 23 to >95percent.Upon hydrolysis the alkylation products 5-7 furnished the optically active α-alkylated methyl (S)-valinates 8, -leucinates 10, and -isoleucinates 11.