1073238-43-3

Basic information

• Product Name: 1-(4-chlorobenzyl)-3-[2-(3,3-difluoropyrrolidin-1-yl)-2-oxoethyl]-8-ethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione
• Synonyms: 1-(4-chlorobenzyl)-3-[2-(3,3-difluoropyrrolidin-1-yl)-2-oxoethyl]-8-ethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione
• CAS NO: 1073238-43-3
• Molecular Weight: 465.887
• Mol File: 1073238-43-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(4-chlorobenzyl)-3-[2-(3,3-difluoropyrrolidin-1-yl)-2-oxoethyl]-8-ethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-chlorobenzyl)-3-[2-(3,3-difluoropyrrolidin-1-yl)-2-oxoethyl]-8-ethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione(1073238-43-3)
• EPA Substance Registry System: 1-(4-chlorobenzyl)-3-[2-(3,3-difluoropyrrolidin-1-yl)-2-oxoethyl]-8-ethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione(1073238-43-3)

Safety Data

• Hazardous Substances Data: 1073238-43-3(Hazardous Substances Data)

Upstream product

• 1073237-98-5 methyl [1-(4-chlorobenzyl)-8-ethyl-7-methyl-2,6-dioxo-1,2,6,7-tetrahydro-3H-purin-3-yl]acetate 
• 1073239-10-7 [1-(4-chlorobenzyl)-8-ethyl-7-methyl-2,6-dioxo-1,2,6,7-tetrahydro-3H-purin-3-yl] acetic acid 
• 163457-23-6 3,3-difluoropyrrolidine hydrochloride 

Relevant articles and documents

XANTHINE COMPOUNDS HAVING A POSITIVE ALLOSTERIC GABAB RECEPTOR MODULATOR EFFECT

The present invention relates to novel xanthine compounds of the general formula (I) wherein R1, R2, R3 and R4 are as defined, having a positive allosteric GABA Breceptor (GBR) modulator effect, methods for the preparation of said compounds and to their use, optionally in combination with a GABA Bagonist, for the inhibition of transient lower esophageal sphincter relaxations, for the treatment of gastroesophageal reflux disease, as well as for the treatment of functional gastrointestinal disorders and irritable bowel syndrome (IBS).