1074-62-0

Basic information

• Product Name: 4-(Aminomethyl)cyclohexanemethanol
• Synonyms: 4-(Aminomethyl)cyclohexanemethanol
• CAS NO: 1074-62-0
• Molecular Formula: C₈H₁₇NO
• Molecular Weight: 143.23
• Mol File: 1074-62-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 243.4°C at 760 mmHg
• Flash Point: 101°C
• Appearance: /
• Density: 0.956g/cm³
• Vapor Pressure: 0.00544mmHg at 25°C
• Refractive Index: 1.474
• CAS DataBase Reference: 4-(Aminomethyl)cyclohexanemethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(Aminomethyl)cyclohexanemethanol(1074-62-0)
• EPA Substance Registry System: 4-(Aminomethyl)cyclohexanemethanol(1074-62-0)

Safety Data

• Hazardous Substances Data: 1074-62-0(Hazardous Substances Data)

Usage

General Description

4-(Aminomethyl)cyclohexanemethanol is a chemical compound with the molecular formula C8H17NO. It is a cyclohexane derivative with an amino group attached to the carbon atom. 4-(Aminomethyl)cyclohexanemethanol is commonly used as a pharmaceutical intermediate in the synthesis of various medication such as muscle relaxants and antispasmodics. It has properties that make it suitable for use in the treatment of conditions such as chronic pain, muscle spasms, and neuralgia. Additionally, it is also used in the production of certain types of polymers and resins.

InChI:InChI=1/C8H17NO/c9-5-7-1-3-8(6-10)4-2-7/h7-8,10H,1-6,9H2

Upstream product

• 105-08-8 bis-1,4-(hydroxymethyl)cyclohexane 
• 100-49-2 cyclohexylmethyl alcohol 
• 1197-17-7 4-aminomethyl-cyclohexanecarboxylic acid 

Downstream Products

• 840-84-6 {4-[(2-Chloro-benzylamino)-methyl]-cyclohexyl}-methanol 
• 1018674-46-8 trans-(4-Hydroxymethyl-cyclohexylmethyl)-carbamic acid tert-butyl ester 
• 1018811-89-6 cyclopentyl (2S)-cyclohexyl{[(4-{[(3-{(1E)-3-[(1-isobutoxyethoxy)amino]-3-oxoprop-1-en-1-yl}benzyl)amino]methyl}cyclohexyl)methyl]amino}acetate 
• 1018811-87-4 cyclopentyl (2S)-{[(4-{[(tert-butoxycarbonyl)amino]methyl}cyclohexyl)methyl]amino}(cyclohexyl)acetate 
• 1018811-88-5 cyclopentyl (2S)-({[4-(aminomethyl)cyclohexyl]methyl}amino)(cyclohexyl)acetate 
• 916210-80-5 trans-4-(N-tert-butoxycarbonylaminomethyl)cyclohexane carboxaldehyde 
• 7006-45-3 N-Benzyl-1-benzyloxymethyl-4-cyclohexanemethylamine 
• 729-51-1 (2-Chloro-benzyl)-(4-chloromethyl-cyclohexylmethyl)-amine 
• 726-54-5 4-Benzylaminomethylcyclohexylmethylchlorid 

Relevant articles and documents

Steric effects in the catalytic amination of γ-, δ-, and ε-glycols

The amination of butane-1,4-diol, isomeric dipropylene glycols, and cyclohexane-1,4-diyldimethanol in the presence of nickel/copper/chromium catalysts has been studied. The effect of the initial glycol structure on the reaction selectivity has been estima

CYCLOHEXANEDIMETHANAMINE BY DIRECT AMINATION OF CYCLOHEXANEDIMETHANOL

Embodiments of the present invention include methods for producing a cyclohexanedimethanamine by a reductive amination process.

HDAC INHIBITORS

Compounds of formula (I) inhibit HDAC activity, wherein A, B and D independently represent =C- or =N-; W is a divalent radical -CH=CH- or CH2CH2-; R1 is a carboxylic acid group (-COOH), or an ester group which is hydrolysable by one or more intracellular carboxyesterase enzymes to a carboxylic acid group; R2 is the side chain of a natural or non-natural alpha amino acid; z is 0 or 1; and Y, L1, and X1 are as defined in the claims.