1074365-84-6 Usage
Description
Apixaban Impurity 6, also known as 4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-Pyrazolo[3,4-c]pyridine-3-carboxylic Acid Methyl Ester, is an impurity found in Apixaban (A726700), which is an active inhibitor of coagulation factor Xa. This impurity is a synthetic organic compound that may be present during the manufacturing process of Apixaban.
Uses
Used in Pharmaceutical Industry:
Apixaban Impurity 6 is used as a reference compound for quality control and analytical purposes in the pharmaceutical industry. It helps ensure the purity and efficacy of Apixaban, a medication used to treat and prevent blood clots.
Apixaban Impurity 6 is used as a research tool for studying the structure-activity relationship of Apixaban and its analogs. This helps scientists understand the molecular interactions and optimize the drug's therapeutic potential.
Additionally, Apixaban Impurity 6 may be used in the development of new drugs targeting coagulation factor Xa, as understanding the properties of impurities can contribute to the design of more effective and safer medications.
Check Digit Verification of cas no
The CAS Registry Mumber 1074365-84-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,7,4,3,6 and 5 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1074365-84:
(9*1)+(8*0)+(7*7)+(6*4)+(5*3)+(4*6)+(3*5)+(2*8)+(1*4)=156
156 % 10 = 6
So 1074365-84-6 is a valid CAS Registry Number.
1074365-84-6Relevant articles and documents
A mechanistic study on the amidation of esters mediated by sodium formamide
Ramirez, Antonio,Mudryk, Boguslaw,Rossano, Lucius,Tummala, Srinivas
, p. 775 - 779 (2012)
Kinetic and computational studies on the amidation of esters with mixtures of formamide and sodium methoxide are described. Rate studies are consistent with a fast deprotonation of formamide followed by two reversible acyl transfers affected by solvent pa