107627-09-8

Basic information

• Product Name: 1,4-bis(4-methoxyphenyl)butan-2-one
• Synonyms: 1,4-bis(4-methoxyphenyl)butan-2-one
• CAS NO: 107627-09-8
• Molecular Weight: 284.355
• Mol File: 107627-09-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,4-bis(4-methoxyphenyl)butan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-bis(4-methoxyphenyl)butan-2-one(107627-09-8)
• EPA Substance Registry System: 1,4-bis(4-methoxyphenyl)butan-2-one(107627-09-8)

Safety Data

• Hazardous Substances Data: 107627-09-8(Hazardous Substances Data)

Upstream product

• 5720-07-0 4-methoxyphenylboronic acid 
• 2393-23-9 4-methoxy-benzylamine 
• 1929-29-9 3-(4-methoxyphenyl)propanoic acid 
• 15893-42-2 3-(4-methoxyphenyl)propionyl chloride 
• 71017-75-9 1-(4-methoxybenzyl)-2,4,6-triphenylpyridin-1-ium tetrafluoroborate salt 
• 123-11-5 4-methoxy-benzaldehyde 
• 122-84-9 4-methoxybenzyl methyl ketone 
• 110435-88-6 1,4t-bis-(4-methoxy-phenyl)-but-3-en-2-one 

Relevant articles and documents

Utility of Organoboron Reagents in Arylation of Cyclopropanols via Chelated Pd(II) Catalysis: Chemoselective Access to β-Aryl Ketones

Organoborane reagents were investigated as coupling partners to cyclopropanol-derived β-ketone enolates in the presence of a chelated Pd(II) catalyst. Efficient coupling of a range of electronically and sterically diverse cyclopropanols and aryl/alkenyl boronic derivatives (39 examples, 65-94% yield) could be achieved with the generation of synthetically important β-aryl ketone intermediates in a chemoselective fashion. This reactivity paradigm, which broadens the scope of aryl donor partners to homoenolates, allows open-flask conditions, water as a cosolvent, and preparation of halogen-bearing β-aryl ketones that are distinct from previous methods. This chelated Pd(II) catalysis appears to be different from the Pd(0) pathway, as evident from deuterium scrambling studies that could reveal differentiating protonolysis of an α-keto carbopalladium complex in the terminal step.