1079054-23-1Relevant articles and documents
Structural features of phenoxycarbonylimino neonicotinoids acting at the insect nicotinic receptor
Ohno, Ikuya,Tomizawa, Motohiro,Miyazu, Nozomi,Kushibiki, Gohito,Noda, Kumiko,Hasebe, Yasunori,Durkin, Kathleen A.,Miyake, Taiji,Kagabu, Shinzo
scheme or table, p. 5933 - 5935 (2010/11/18)
Substituted-phenoxycarbonylimino neonicotinoid ligands with an electron-donating group showed significantly higher affinity to the insect nicotinic receptor relative to that of the analogue with an electron-withdrawing substituent, thereby establishing in silico binding site interaction model featuring that the phenoxy ring of neonicotinoids and the receptor loop D tryptophan indole plane form a face-to-edge aromatic interaction.