108149-62-8 Usage
Description
(4S,5R)-4-ForMyl-2,2,5-triMethyl-3-oxazolidinecarboxylic Acid 1,1-DiMethylethyl Ester, also known as tert-Butyl (4S,5R)-4-formyl-2,2,5-trimethyl-1,3-oxazolidine-3-carboxylate, is a versatile organic compound with a unique molecular structure. It is characterized by its chiral centers at the 4S and 5R positions, which contribute to its stereoselective properties. (4S,5R)-4-ForMyl-2,2,5-triMethyl-3-oxazolidinecarboxylic Acid 1,1-DiMethylethyl Ester is widely utilized in the synthesis of various complex molecules, particularly in the pharmaceutical and chemical industries.
Uses
Used in Pharmaceutical Industry:
(4S,5R)-4-ForMyl-2,2,5-triMethyl-3-oxazolidinecarboxylic Acid 1,1-DiMethylethyl Ester is used as a key intermediate in the stereoselective synthesis of (E)-alkene dipeptide isoteres. Its unique structure allows for the creation of complex molecular architectures with high selectivity, which is crucial for the development of new drugs with improved efficacy and reduced side effects.
Used in Chemical Industry:
(4S,5R)-4-ForMyl-2,2,5-triMethyl-3-oxazolidinecarboxylic Acid 1,1-DiMethylethyl Ester is used as a building block in the synthesis of amino sugars and sphingosines. Amino sugars are essential components of various biological molecules, such as glycoproteins and glycolipids, which play vital roles in cellular recognition, signaling, and immune responses. Sphingosines are important components of cell membranes and are involved in various cellular processes, including cell growth, differentiation, and apoptosis. The use of this compound in their synthesis enables the development of novel bioactive molecules with potential applications in the treatment of various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 108149-62-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,8,1,4 and 9 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 108149-62:
(8*1)+(7*0)+(6*8)+(5*1)+(4*4)+(3*9)+(2*6)+(1*2)=118
118 % 10 = 8
So 108149-62-8 is a valid CAS Registry Number.
108149-62-8Relevant articles and documents
MEAYAMYCIN ANALOGUES AND METHODS OF USE
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, (2021/10/15)
Compounds according to formula (I), where R is as defined herein, have anti-cancer properties.
THAILANSTATIN ANALOGS
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Paragraph 0330; 0331, (2019/04/05)
The invention provides novel cytotoxic compounds and cytotoxic conjugates comprising these cytotoxic compounds and cell-binding agents. More specifically, this invention relates to novel thailanstatin A analogs, useful as cytotoxic small molecule toxins i
From the Feist-Bénary reaction to organocatalytic domino Michael-alkylation reactions: Asymmetric synthesis of 3(2H)-furanones
Dou, Xiaowei,Han, Xiaoyu,Lu, Yixin
supporting information; experimental part, p. 85 - 89 (2012/02/04)
It all adds up! A modified Feist-Bénary reaction employing a domino Michael-alkylation sequence was designed for the enantioselective synthesis of 3(2H)-furanones. L-Threonine-derived tertiary amine/thiourea catalysts were prepared for the first time; such catalysts promoted the designed domino Michael-alkylation reactions in a highly enantioselective manner (see scheme). Copyright