108380-28-5

Basic information

• Product Name: (S)-5-(2-(benzyloxy)ethyl)dihydrofuran-2(3H)-one
• Synonyms: (S)-5-(2-(benzyloxy)ethyl)dihydrofuran-2(3H)-one
• CAS NO: 108380-28-5
• Molecular Weight: 220.268
• Mol File: 108380-28-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (S)-5-(2-(benzyloxy)ethyl)dihydrofuran-2(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-5-(2-(benzyloxy)ethyl)dihydrofuran-2(3H)-one(108380-28-5)
• EPA Substance Registry System: (S)-5-(2-(benzyloxy)ethyl)dihydrofuran-2(3H)-one(108380-28-5)

Safety Data

• Hazardous Substances Data: 108380-28-5(Hazardous Substances Data)

Upstream product

• 4613-62-1 3-deoxy-1,2;5,6-di-O-isopropylidene-α-D-glucofuranoside 
• 108380-26-3 Methyl 6-O-benzyl-3,5-dideoxy-2-methylthiocarbonyl (α- and β-)-D-erythrohexofuranoside 
• 108380-24-1 6-O-Benzyl-3,5-dideoxy-1,2-O-isopropylidene-α-D-erythro-hexofuranose 
• 96852-87-8 1,2-O-isopropylidene-3-deoxy-5,6-di-O-methylsulphonyl-α-D-glucofuranose 
• 96852-88-9 3,5,6-trideoxy-1,2-O-isopropylidene-α-D-ribo-hex-5-enofuranoside 
• 4005-46-3 3-deoxy-1,2-O-isopropylidene-D-glucose 
• 6027-62-9 3-deoxy-3-iodo-1,2:5,6-di-O-isopropylidene-α-D-allofuranose 
• 58475-20-0 3,5-dideoxy-1,2-O-isopropylidene-α-D-erythro-hexofuranose 
• 108380-27-4 Methyl 6-O-benzyl-2,3,5-trideoxy-(α,β)-D-glycerohexofuranoside 
• 108380-29-6 (S)-5-(2-Benzyloxy-ethyl)-tetrahydro-furan-2-ol 

Relevant articles and documents

Iridium-Catalyzed C-C Coupling of a Simple Propargyl Ether with Primary Alcohols: Enantioselective Homoaldol Addition via Redox-Triggered (Z)-Siloxyallylation

A chiral iridium complex formed in situ from [Ir(cod)Cl]2 and (R)-H8-BINAP is found to catalyze the direct enantioselective C-C coupling of a simple propargyl ether, TIPSOCH2C-CH, with primary alcohols to form γ-hydroxy (Z)-enol silanes with uniformly high enantioselectivity and complete alkene (Z)-stereoselectivity. As corroborated by deuterium labeling studies, these studies represent the first examples of 1,2-hydride shift-enabled π-allyl formation in the context of iridium catalysis.

A direct method for the conversion of terminal epoxides into γ-butanolides

A new and efficient process for the conversion of terminal epoxides to γ-butanolides is described involving Lewis acid promoted epoxide ring-opening by 1-morpholino-2-trimethylsilyl acetylene. Addition of a terminal epoxide to a solution of the ynamine an