1086-20-0Relevant articles and documents
Chemoselective: N -arylation of aminobenzamides via copper catalysed Chan-Evans-Lam reactions
Liu, Shuai,Zu, Weisai,Zhang, Jinli,Xu, Liang
, p. 9288 - 9292 (2017/11/23)
Chemoselective N-arylation of unprotected aminobenzamides was achieved via Cu-catalysed Chan-Evans-Lam cross-coupling with aryl boronic acids for the first time. Simple copper catalysts enable the selective arylation of amino groups in ortho/meta/para-aminobenzamides under open-flask conditions. The reactions were scalable and compatible with a wide range of functional groups.